1 - 1st generation cephalosporin is________________?
1 - 1st generation cephalosporin is________________?
Cephadroxil
2 - A child with permanently stained teeth reports, He was most probably administered_____________?
2 - A child with permanently stained teeth reports, He was most probably administered_____________?
Doxycycline
3 - A diabetic patient developed cellulitis due to Staphylococcus aureus, Which was found to be Methicillin resistant on the antibiotic sensitivity testing. All the following antibiotics will be appropriate except_____________?
3 - A diabetic patient developed cellulitis due to Staphylococcus aureus, Which was found to be Methicillin resistant on the antibiotic sensitivity testing. All the following antibiotics will be appropriate except_____________?
Imipenem
4 - A distinict advantage that tetracyclines have over penicillins is that tetracyclines_____________?
4 - A distinict advantage that tetracyclines have over penicillins is that tetracyclines_____________?
Have a wider range of antibacterial activity
5 - A patient has seasonal allergic rhinitis and is on terfenadine, He develps cardiac arrhythmias after a course of antibiotics. Which of the following antibiotic could have been given_____________?
5 - A patient has seasonal allergic rhinitis and is on terfenadine, He develps cardiac arrhythmias after a course of antibiotics. Which of the following antibiotic could have been given_____________?
Erythromycin
6 - A patient suffering from syphilis is given pencillin He may develop_____________?
6 - A patient suffering from syphilis is given pencillin He may develop_____________?
Jarish – Herxheimer reaction
7 - A patient taking which of the following drug should not eat cheese, etc_____________?
7 - A patient taking which of the following drug should not eat cheese, etc_____________?
Tetracycline
8 - A potent non-texic anti-herpes drug is_______________?
8 - A potent non-texic anti-herpes drug is_______________?
Acyclovir
9 - Agent used in oral thrush_____________?
9 - Agent used in oral thrush_____________?
Clotrimazole
10 - AIDS is a disease if the immune system primarily affecting_____________?
10 - AIDS is a disease if the immune system primarily affecting_____________?
T lymphocytes
11 - All are macrolide antibiotics EXCEPT______________?
11 - All are macrolide antibiotics EXCEPT______________?
Neomycin
12 - All except one are centrally acting muscle blocks___________?
12 - All except one are centrally acting muscle blocks___________?
Dantrolene sodium
13 - All of the following antibacterial agents acts by inhibiting cell wall systhesis except________________?
13 - All of the following antibacterial agents acts by inhibiting cell wall systhesis except________________?
Nitrofurantoins
14 - All of the following are features of streptomycin drug except______________?
14 - All of the following are features of streptomycin drug except______________?
It can be given orally
15 - All of the following are therapeutic uses of penicillin G, except_____________?
15 - All of the following are therapeutic uses of penicillin G, except_____________?
Rickettsial infection
16 - All of the following are topically used sulphonamides except____________?
16 - All of the following are topically used sulphonamides except____________?
Sulphadiazine
17 - All of the following cephalosporines are active against Pseudomonas Except_____________?
17 - All of the following cephalosporines are active against Pseudomonas Except_____________?
Cefaclor
18 - All of the following drugs are components of the MOPP cancer Chemotherapy regimen EXCEPT______________?
18 - All of the following drugs are components of the MOPP cancer Chemotherapy regimen EXCEPT______________?
Methotrexate
19 - All of the following drugs are contraindicated in patients with G-6-PD deficiency, except____________?
19 - All of the following drugs are contraindicated in patients with G-6-PD deficiency, except____________?
Ceftriaxone
20 - All of the following drugs are primarily bacteriostatic except______________?
20 - All of the following drugs are primarily bacteriostatic except______________?
Rifampin
21 - All of the following statement about antimalarial drugs are correct except_____________?
21 - All of the following statement about antimalarial drugs are correct except_____________?
Mefloquine may safely be given to air pilots
22 - Amino glycosides_______________?
22 - Amino glycosides_______________?
All of the above
23 - Among the drugs given below, which is LEAST likely to be implicated in drug induced hepatitis ?
23 - Among the drugs given below, which is LEAST likely to be implicated in drug induced hepatitis ?
Streptomycin
24 - Amphotericin B is given for what etiology_______________?
24 - Amphotericin B is given for what etiology_______________?
Fungal
25 - An aminoglycoside that is often combined with polymyxin and bacitracin for the treatment of topical infection is____________?
25 - An aminoglycoside that is often combined with polymyxin and bacitracin for the treatment of topical infection is____________?
Neomycin
26 - Antibiotic that achieves high concentration in Hard tissue, because of its molecular size is______________?
26 - Antibiotic that achieves high concentration in Hard tissue, because of its molecular size is______________?
Clindamycin
27 - Antibiotic that interferes with DNA function is_____________?
27 - Antibiotic that interferes with DNA function is_____________?
Metronidazole
28 - Antifungal drug not used in the treatment of imtestinal candidiasis______________?
28 - Antifungal drug not used in the treatment of imtestinal candidiasis______________?
Clotrimazole
29 - Bacitracin is a_______________?
29 - Bacitracin is a_______________?
Topical antibiotic
30 - Best treatment of candidiasis of_____________?
30 - Best treatment of candidiasis of_____________?
Mycostatin
31 - B-lactam antibiotics are_____________?
31 - B-lactam antibiotics are_____________?
All of the above
32 - Cell wall synthesis is inhibited by all except____________?
32 - Cell wall synthesis is inhibited by all except____________?
Lincomycin
33 - Cephalosporin active against pseudomonas aeruginosa______________?
33 - Cephalosporin active against pseudomonas aeruginosa______________?
Cefoperazone
34 - Cephalosporines have all of the following interactions except_____________?
34 - Cephalosporines have all of the following interactions except_____________?
Are penicillinase resistant
35 - Chloramphenicol can cause_____________?
35 - Chloramphenicol can cause_____________?
B & C
36 - Clavulanic acid added to ampicillin causes_____________?
36 - Clavulanic acid added to ampicillin causes_____________?
Inhibition of B-lactamases
37 - Clavulanic acid is given in combination with amoxicillin in order to____________?
37 - Clavulanic acid is given in combination with amoxicillin in order to____________?
Extend amoxicillin's antibacterial spectrum
38 - Colour of teeth stained by tetracycline appear _________ under UV light?
38 - Colour of teeth stained by tetracycline appear _________ under UV light?
Yellow
39 - Combination chemotherapy is used in tuberculosis in order to reduce____________?
39 - Combination chemotherapy is used in tuberculosis in order to reduce____________?
Development of drug resistance
40 - Concurrent administration of tetracyclines is most likely to impair the action of_____________?
40 - Concurrent administration of tetracyclines is most likely to impair the action of_____________?
Penicillin
41 - Cross resistance of isoniazid is seen with_____________?
41 - Cross resistance of isoniazid is seen with_____________?
Ethionamide
42 - Cyclosporin is used an______________?
42 - Cyclosporin is used an______________?
Immunosuppresant
43 - Desfuroxamide is a drug used for____________?
43 - Desfuroxamide is a drug used for____________?
Thalassemia
44 - Disseminated candidiasis requires intensive therapy with_____________?
44 - Disseminated candidiasis requires intensive therapy with_____________?
Amphotericin
45 - Drug chemically related to penicillins is_____________?
45 - Drug chemically related to penicillins is_____________?
Cephalosporin
46 - Drug of choice in Amoebic liver abscess besides metronidazole is_____________?
46 - Drug of choice in Amoebic liver abscess besides metronidazole is_____________?
Chloroquin
47 - Drug of choice to treat fungal infection in AIDS is_____________?
47 - Drug of choice to treat fungal infection in AIDS is_____________?
Ketoconazole
48 - Drug to be avoided in a patient allergic to penicillin is_____________?
48 - Drug to be avoided in a patient allergic to penicillin is_____________?
Ampicillin
49 - Drug which is most unsafe during pregnancy is____________?
49 - Drug which is most unsafe during pregnancy is____________?
B & C
50 - Drugs producing ototoxicity and Nephro toxicity are______________?
50 - Drugs producing ototoxicity and Nephro toxicity are______________?
Aminoglycosides
51 - Drugs which cause ototoxicity and circumoral paraesthesia are______________?
51 - Drugs which cause ototoxicity and circumoral paraesthesia are______________?
Streptomycin
52 - Each of the following statement is correct about metronidazole EXCEPT that it_______________?
52 - Each of the following statement is correct about metronidazole EXCEPT that it_______________?
An effective alternative for infection caused by aerobic gram positive cocci
53 - Erythromycin is_______________?
53 - Erythromycin is_______________?
Cidal in high concentration
54 - First line of antitubercular drug is_____________?
54 - First line of antitubercular drug is_____________?
INH
55 - Fluconazole is used for the treatment of______________?
55 - Fluconazole is used for the treatment of______________?
Candidiasis
56 - Following antimicrobials are termed as type I calcimimetics that mimic the stimulatory effect of calcium, on the calcium sensing receptor to inhibit PTH secretion by the parathyroid gland EXCEPT______________?
56 - Following antimicrobials are termed as type I calcimimetics that mimic the stimulatory effect of calcium, on the calcium sensing receptor to inhibit PTH secretion by the parathyroid gland EXCEPT______________?
Hamycin
57 - Granesetron, the antiemetic properties because of____________?
57 - Granesetron, the antiemetic properties because of____________?
Serotonin receptor – blocking action
58 - Identify the drugs useful against pseudomonanas infection______________?
58 - Identify the drugs useful against pseudomonanas infection______________?
All of the above
59 - IF a bacteria were susceptible to both penicillin and Erythromycin, then it would not be appropriate to treat the patients with both antibiotics at the same time because_______________?
59 - IF a bacteria were susceptible to both penicillin and Erythromycin, then it would not be appropriate to treat the patients with both antibiotics at the same time because_______________?
Penicillin is only effective against growing cells
60 - In the treatment of intestinal of intestinal and extraintestinal amoebiasis which of the following drug is useful____________?
60 - In the treatment of intestinal of intestinal and extraintestinal amoebiasis which of the following drug is useful____________?
Metronidazole
61 - INH induced neuropathy is treated with______________?
61 - INH induced neuropathy is treated with______________?
Pyridoxine
62 - Ivermectin is indicated in_____________?
62 - Ivermectin is indicated in_____________?
All of the above
63 - Jerisch-Heximer reaction is treated by administering______________?
63 - Jerisch-Heximer reaction is treated by administering______________?
Antihistamines
64 - Ketoconazole______________?
64 - Ketoconazole______________?
Antifungal agent
65 - Mechanism of action of beta-lactam antibiotics would be______________?
65 - Mechanism of action of beta-lactam antibiotics would be______________?
Inhibition of cell wall peptidoglycan synthesis by competitive inhibition of transpetidases
66 - Mechanism of action of chlortetracycline_____________?
66 - Mechanism of action of chlortetracycline_____________?
Inhibition of protein synthesis
67 - Mechanism of action of quinolones is______________?
67 - Mechanism of action of quinolones is______________?
Inhibits DNA gyrase
68 - Metronidazole is a type of___________?
68 - Metronidazole is a type of___________?
Imidazole derivative
69 - Metronidazole______________?
69 - Metronidazole______________?
Is used in management of ANUG
70 - More potent and non toxic drug against herpes virus is_____________?
70 - More potent and non toxic drug against herpes virus is_____________?
Acyclovir
71 - Nevirapine is a______________?
71 - Nevirapine is a______________?
Non-nucleoside reverse transcriptase inhibitor
72 - Not true about piperacilline is_______________?
72 - Not true about piperacilline is_______________?
Inhibits Beta-lactamase
73 - Not true about PnG is______________?
73 - Not true about PnG is______________?
More concentrated in prostatic secretion and intraocular fluids
74 - One of the below mentioned penicillin is NOT given orally______________?
74 - One of the below mentioned penicillin is NOT given orally______________?
Carbenicillin
75 - One of the drug is betalactamase inhibitor_____________?
75 - One of the drug is betalactamase inhibitor_____________?
Sulbactum
76 - One of the following is not penicillinase susceptible______________?
76 - One of the following is not penicillinase susceptible______________?
Cloxacillin
77 - Optic neuritis is a side effect of______________?
77 - Optic neuritis is a side effect of______________?
Ethambutol
78 - Oral contraceptive failure occurs in a patient on Rifampicin because of____________?
78 - Oral contraceptive failure occurs in a patient on Rifampicin because of____________?
Rifampicin induce the metabolism of contra ceptive
79 - Oral infection by penicillinase producing organisms should be treated with____________?
79 - Oral infection by penicillinase producing organisms should be treated with____________?
Dicloxacillin
80 - Ototoxicity and nephrotoxicity is caused by______________?
80 - Ototoxicity and nephrotoxicity is caused by______________?
antibiotic
81 - Penicillin is effective against_____________?
81 - Penicillin is effective against_____________?
All of the above
82 - Peripheral neuritis is a complication of_______________?
82 - Peripheral neuritis is a complication of_______________?
Isoniazid
83 - Phototoxicity is the side effect of_____________?
83 - Phototoxicity is the side effect of_____________?
Demeclocycline
84 - Povidine iodine is used for_____________?
84 - Povidine iodine is used for_____________?
All of the above
85 - Prolonged administration of streptomycin may result in damage to the____________?
85 - Prolonged administration of streptomycin may result in damage to the____________?
Auditory nerve
86 - Redman syndrome is side effect of______________?
86 - Redman syndrome is side effect of______________?
Vancomycin
87 - Roxithromycin is______________?
87 - Roxithromycin is______________?
A long acting macrolide
88 - Slufonamides mainly interferes with the bacterial______________?
88 - Slufonamides mainly interferes with the bacterial______________?
PABA
89 - Stepwise mutation for drug resistance is seen with_____________?
89 - Stepwise mutation for drug resistance is seen with_____________?
Penicillin
90 - Tetracycline acts on______________?
90 - Tetracycline acts on______________?
30S ribosomes
91 - Tetracycline chelates with______________?
91 - Tetracycline chelates with______________?
All of the above
92 - Tetracycline in children causes____________?
92 - Tetracycline in children causes____________?
Discolored teeth
93 - Tetracycline is contraindicated in_____________?
93 - Tetracycline is contraindicated in_____________?
All of the above
94 - Tetracycline is more preferred in periodontics because______________?
94 - Tetracycline is more preferred in periodontics because______________?
All of the above
95 - Tetracycline when given to pregnant woman can cause_______________?
95 - Tetracycline when given to pregnant woman can cause_______________?
Discoloration/ staining of hard structures of foetus
96 - Tetracyclines act by__________________?
96 - Tetracyclines act by__________________?
Inhibiting the binding of aminoacyl tRNA to the ribosomal complex
97 - The administration of penicillin G along with probenicid result in_____________?
97 - The administration of penicillin G along with probenicid result in_____________?
Decreased renal excretion of penciling G
98 - The aminoglycoside with least toxic effect is_____________?
98 - The aminoglycoside with least toxic effect is_____________?
Streptomycin
99 - The antibiotic of choice in patients sensitive to penicillin is___________?
99 - The antibiotic of choice in patients sensitive to penicillin is___________?
Erythromycin
100 - The bacterial resistance to tetracycline is due to___________?
100 - The bacterial resistance to tetracycline is due to___________?
Inactivation of drug by enzymes
101 - The drug for choice for treatment of infection involving non-penicillinase producing staphylococcus is___________?
101 - The drug for choice for treatment of infection involving non-penicillinase producing staphylococcus is___________?
Penicilling G
102 - The drug for choice for treatment of infection involving non-penicillinase producing staphylococcus is______________?
102 - The drug for choice for treatment of infection involving non-penicillinase producing staphylococcus is______________?
Penicilling G
103 - The drug of choice for treatment of tyhoid is____________?
103 - The drug of choice for treatment of tyhoid is____________?
Ciprofloxacin
104 - The drug which gives orange colour to the urine is______________?
104 - The drug which gives orange colour to the urine is______________?
Rifampicin
105 - The following adverse effect of penicillin is dose related___________?
105 - The following adverse effect of penicillin is dose related___________?
Encephalopathy
106 - The following are the indications for Metronidazole except_____________?
106 - The following are the indications for Metronidazole except_____________?
Streptococcal sore throat
107 - The group of antibiotics which possess additional anti-inflammatory and immunomodulatory activities is_____________?
107 - The group of antibiotics which possess additional anti-inflammatory and immunomodulatory activities is_____________?
Macrolides
108 - The incidence of allergy to penicillin among various population ranges from______________?
108 - The incidence of allergy to penicillin among various population ranges from______________?
1% to 10%
109 - The mechanism of action of chloramphenicol is inhibition of synthesis of_____________?
109 - The mechanism of action of chloramphenicol is inhibition of synthesis of_____________?
Protein
110 - The most common side effect of the oral administration of ampicillin is_______________?
110 - The most common side effect of the oral administration of ampicillin is_______________?
Diarrhoea
111 - The most preferred acute emetic for emesis induced by anticancer drugs is______________?
111 - The most preferred acute emetic for emesis induced by anticancer drugs is______________?
Ondensetron
112 - The most serious side effect of drug chloramp henicol is______________?
112 - The most serious side effect of drug chloramp henicol is______________?
Bone marrow depression
113 - The oral microblal fiora of a patient on prolonged broad spectrume antibiotic therapy is predominantly____________?
113 - The oral microblal fiora of a patient on prolonged broad spectrume antibiotic therapy is predominantly____________?
Yeast and fungi
114 - The oropharyngeal and oesophageal candidiasis following long-term therapy with a broad spectrum antibiotic can be best treated with____________?
114 - The oropharyngeal and oesophageal candidiasis following long-term therapy with a broad spectrum antibiotic can be best treated with____________?
Fluconazole
115 - The therapeutic advantage that pencillin V has over pencillin G is____________?
115 - The therapeutic advantage that pencillin V has over pencillin G is____________?
More reliable oral obsorption
116 - Topical Antifungal agent in candidiasis is______________?
116 - Topical Antifungal agent in candidiasis is______________?
Clotrimazole
117 - Traces of which of the antibiotics can be found in the gingival fluid after administration___________?
117 - Traces of which of the antibiotics can be found in the gingival fluid after administration___________?
Tetracycline
118 - True about aminoglycoside is all except______________?
118 - True about aminoglycoside is all except______________?
Are bacteriostatic
119 - True about amoxycillin in comparison to ampicillin is_______________?
119 - True about amoxycillin in comparison to ampicillin is_______________?
Higher oral biovailability
120 - When broad spectrum antibiotics are administered with coumarin anticoagulants, the anticoagulant action may be____________?
120 - When broad spectrum antibiotics are administered with coumarin anticoagulants, the anticoagulant action may be____________?
Increased because of reduction of vitamin sources
121 - Which among the drugs given below, does Not act by protease inhibition ?
121 - Which among the drugs given below, does Not act by protease inhibition ?
Zanamivir
122 - Which among the following anti-HIV drugs in an inhibitor of viral fusion ?
122 - Which among the following anti-HIV drugs in an inhibitor of viral fusion ?
Enfuvirtide
123 - Which among the following anti-HIV drugs is also used to treat viral hepatitis B ?
123 - Which among the following anti-HIV drugs is also used to treat viral hepatitis B ?
Lamivudine
124 - Which among the following is the drug of choice for clostridium difficile induced colitis ?
124 - Which among the following is the drug of choice for clostridium difficile induced colitis ?
Metronidazole
125 - Which anti tubercullar drug will cause transjent memory loss ?
125 - Which anti tubercullar drug will cause transjent memory loss ?
INH
126 - Which antibiotic is effective against pseudomonas and indole +ve proteus ?
126 - Which antibiotic is effective against pseudomonas and indole +ve proteus ?
Carbenicillin
127 - Which drug can be safely used in lactating mothers ?
127 - Which drug can be safely used in lactating mothers ?
Erythromycin
128 - Which drug causes photosensitivity______________?
128 - Which drug causes photosensitivity______________?
Tetracycline
129 - Which of the following antibiotics is effective in treating oral candidiasis ?
129 - Which of the following antibiotics is effective in treating oral candidiasis ?
Nystatin
130 - Which of the following antibiotics is found at much higher concentrations in cervicular fluid than in serum ?
130 - Which of the following antibiotics is found at much higher concentrations in cervicular fluid than in serum ?
Tetracyline
131 - Which of the following antibiotics is most frequently associated with pseudomembranous colitis ?
131 - Which of the following antibiotics is most frequently associated with pseudomembranous colitis ?
Clindamycin
132 - Which of the following antibiotics is not used in the treatment of infectious mononucleosis ?
132 - Which of the following antibiotics is not used in the treatment of infectious mononucleosis ?
Gentamycin
133 - Which of the following can be given as a single dose antimalarial for P.vivax malaria______________?
133 - Which of the following can be given as a single dose antimalarial for P.vivax malaria______________?
Pyrimethamine + Sulfadoxime
134 - Which of the following drug control lepramin reaction____________?
134 - Which of the following drug control lepramin reaction____________?
Clofazimine
135 - Which of the following drug does not show renal toxicity_____________?
135 - Which of the following drug does not show renal toxicity_____________?
Isoflurane
136 - Which of the following drugs in likely to damage the eighth cranial nerve when administered for a long period of time ?
136 - Which of the following drugs in likely to damage the eighth cranial nerve when administered for a long period of time ?
Streptomycin
137 - Which of the following is a 4th generation cephalosporin______________?
137 - Which of the following is a 4th generation cephalosporin______________?
Cefepime
138 - Which of the following is a characteristic of tetracycline stains ?
138 - Which of the following is a characteristic of tetracycline stains ?
Stained teeth fluoresce light yellow under U.V light
139 - Which of the following is a first generation oral cephalosporin_____________?
139 - Which of the following is a first generation oral cephalosporin_____________?
Cefadroxil
140 - Which of the following is associated with neutropenia ?
140 - Which of the following is associated with neutropenia ?
Methotrexate
141 - Which of the following is beta-lactam antibiotic ?
141 - Which of the following is beta-lactam antibiotic ?
Cephalosporins
142 - Which of the following is caused by Amphotericin B____________?
142 - Which of the following is caused by Amphotericin B____________?
Hypo Kalemia
143 - Which of the following is not a broad spectrum antibiotic ?
143 - Which of the following is not a broad spectrum antibiotic ?
Cephalosporins
144 - Which of the following is not uridopenicillin ?
144 - Which of the following is not uridopenicillin ?
Flucloxacillin
145 - Which of the following is primarily a bactericidal drug?
145 - Which of the following is primarily a bactericidal drug?
Gentamicin
146 - Which of the following is the main difference between penicillin V and penicillin G____________?
146 - Which of the following is the main difference between penicillin V and penicillin G____________?
Penicilline-V is more stable gastric acid
147 - Which of the following is third generation cephalosporin ?
147 - Which of the following is third generation cephalosporin ?
Cefeperazone
148 - Which of the following penicillins can be given by IV route ?
148 - Which of the following penicillins can be given by IV route ?
Crystalline
149 - Which of the following penicillins has the best gram negative spectrum ?
149 - Which of the following penicillins has the best gram negative spectrum ?
Ampicillin
150 - Which of the following penicillins is given by oral route ?
150 - Which of the following penicillins is given by oral route ?
Penicillin V / Phenoxymethyl penicillin
151 - Which of the most effective for drug asymptomatic amoebic cysts ?
151 - Which of the most effective for drug asymptomatic amoebic cysts ?
Diloxanide furoate
152 - Which on of the following is penicillinase resistant penicillin_______________?
152 - Which on of the following is penicillinase resistant penicillin_______________?
Cloxacillin
153 - Which one of the following antibacterials should not be used with d-tubocuraine ?
153 - Which one of the following antibacterials should not be used with d-tubocuraine ?
Streptomycin
154 - Which one of the following antibiotics chelates with calcium ?
154 - Which one of the following antibiotics chelates with calcium ?
Tetracycline
155 - Which one of the following drugs is an antipseudomonal penicillin ?
155 - Which one of the following drugs is an antipseudomonal penicillin ?
Piperacillin
156 - While performing a procedure, a resident doctor injures herself with a suture needle that has been used to stitch a patient with HIV infection for 11 years. He has been complaint with therapy for several years and has recently changed tablets because of a
156 - While performing a procedure, a resident doctor injures herself with a suture needle that has been used to stitch a patient with HIV infection for 11 years. He has been complaint with therapy for several years and has recently changed tablets because of a
Ziduvidine and Lamivudine and Indivair
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