1 - A child is below the third percentile for height. Growth velocity is normal, but chronologic age is more than skeletal age. The most likely diagnosis is______________?
1 - A child is below the third percentile for height. Growth velocity is normal, but chronologic age is more than skeletal age. The most likely diagnosis is______________?
Constitutional delay in growth
2 - A child with stunted growth with a stuffed – belly, and short stature with mental retardation is suffering from the deficiency of which of the following______________?
2 - A child with stunted growth with a stuffed – belly, and short stature with mental retardation is suffering from the deficiency of which of the following______________?
Thyroxine
3 - A diet deficient in calcium will result in_____________?
3 - A diet deficient in calcium will result in_____________?
Production of parathyroid hormone and bone resorption
4 - A phaeochromocytoma is a tumour of the____________?
4 - A phaeochromocytoma is a tumour of the____________?
None of the above
5 - Acromegaly is a disorder of____________?
5 - Acromegaly is a disorder of____________?
Excess growth hormone secreting
6 - Adrenal gland has two parts; cortex and medulla. Which of the following is correct______________?
6 - Adrenal gland has two parts; cortex and medulla. Which of the following is correct______________?
Cortex is under the control of ACTH
7 - Adrenaline used for controlling of bleeding during surgery may result in________________?
7 - Adrenaline used for controlling of bleeding during surgery may result in________________?
Cardiac arrhythmias
8 - Aldosterone production is controlled by _____________?
8 - Aldosterone production is controlled by _____________?
Anterior pituitary gland
9 - Aldosterone secretion is increased when there is a fall in____________?
9 - Aldosterone secretion is increased when there is a fall in____________?
Plasma Na+
10 - Aldosterone______________?
10 - Aldosterone______________?
Increases retention of sodium
11 - All are seen in Cushing ‘s syndrome except_______________?
11 - All are seen in Cushing ‘s syndrome except_______________?
Hypoglycemia
12 - All of the following are adverse effects of long- term corticosteroids EXCEPT____________?
12 - All of the following are adverse effects of long- term corticosteroids EXCEPT____________?
Hypoglycemia
13 - All of the following hormones have cell surface receptors except_____________?
13 - All of the following hormones have cell surface receptors except_____________?
Thyroxine
14 - All the following hormones are secreted by adrenal cortex except_______________?
14 - All the following hormones are secreted by adrenal cortex except_______________?
Estriol
15 - All the following hormones bind to cell surface receptors of the target tissues EXCEPT_____________?
15 - All the following hormones bind to cell surface receptors of the target tissues EXCEPT_____________?
Estrogen
16 - Blood coagulation is impaired in___________?
16 - Blood coagulation is impaired in___________?
Tetany
17 - Bone metabolism is controlled by ____________?
17 - Bone metabolism is controlled by ____________?
All of the above
18 - Calcitonin is released by ___________________?
18 - Calcitonin is released by ___________________?
Parafollicular cells of thyroid
19 - Changes in biological activity occurring daily are referred as _________ rhythm?
19 - Changes in biological activity occurring daily are referred as _________ rhythm?
Circadian
20 - Contraceptive action of combined pill is mainly due to_______________?
20 - Contraceptive action of combined pill is mainly due to_______________?
Inhibits ovulation
21 - Cortisol levels are maximum during____________?
21 - Cortisol levels are maximum during____________?
Early morning
22 - Cortisol______________?
22 - Cortisol______________?
Secretion increases following injury
23 - Deficiency of cortisol causes_______________?
23 - Deficiency of cortisol causes_______________?
Addison disease
24 - Due fear which of the following hormones increases rapidly _______________?
24 - Due fear which of the following hormones increases rapidly _______________?
Epinephrine
25 - Endocrine disorder is the primary cause of______________?
25 - Endocrine disorder is the primary cause of______________?
Acromegaly
26 - Endocrine glands that are not influenced by the pituitary gland include the____________?
26 - Endocrine glands that are not influenced by the pituitary gland include the____________?
Adrenal medulla, parathyroids, and the islets of langerhans
27 - Enzymes, which play an important role in calcification are______________?
27 - Enzymes, which play an important role in calcification are______________?
Alkaline phosphatase and pyrophophatase
28 - Epinephrine is most closely related in structure to ____________________?
28 - Epinephrine is most closely related in structure to ____________________?
Tyrosine
29 - Excess of cortisol causes______________?
29 - Excess of cortisol causes______________?
Cushing ‘s syndrome
30 - Features of hypothyroidism does not include______________?
30 - Features of hypothyroidism does not include______________?
Increased risk of infections
31 - Fertilized ovum usually gets attached to the uterus wall in ____________?
31 - Fertilized ovum usually gets attached to the uterus wall in ____________?
1 week
32 - Following are local hormones except___________?
32 - Following are local hormones except___________?
Insulin
33 - following are the features of cretinism, except_____________?
33 - following are the features of cretinism, except_____________?
Normal intelligence
34 - FSH is secreted by_____________?
34 - FSH is secreted by_____________?
Basophils
35 - Function of ADH is________________?
35 - Function of ADH is________________?
Water reabsorption
36 - Glucagon is secreted by ____________?
36 - Glucagon is secreted by ____________?
Alpha cells of pancreas
37 - Glucocorticoids decrease inflammatory reaction by reducing_______________?
37 - Glucocorticoids decrease inflammatory reaction by reducing_______________?
Release of histamine
38 - Glucocorticoids have all the following actions except_______________?
38 - Glucocorticoids have all the following actions except_______________?
Decrease in glucose uptake by the heart
39 - Glucose tolerance test is usually done to assess_____________?
39 - Glucose tolerance test is usually done to assess_____________?
Endocrine Dysfunction of Pancreas
40 - Hormone released during increased stress is_____________?
40 - Hormone released during increased stress is_____________?
Cortisol
41 - Hormone responsible for milk ejection______________?
41 - Hormone responsible for milk ejection______________?
Oxytocin
42 - Hormones FSH & LH of anterior pituitary gland acts on___________________?
42 - Hormones FSH & LH of anterior pituitary gland acts on___________________?
Both Testis and ovaries
43 - Hormones, which stimulate spermatogenesis, are______________?
43 - Hormones, which stimulate spermatogenesis, are______________?
Testosterone and F.S. H
44 - Human chorionic gonadotrophin hormone ( HCG)______________?
44 - Human chorionic gonadotrophin hormone ( HCG)______________?
Can be identified in the urine of pregnant women by immunological technique
45 - Hypercalcemia associated with malignancy is most often mediated by _____________?
45 - Hypercalcemia associated with malignancy is most often mediated by _____________?
Parathyroid hormone related protein (PTHrP)
46 - Hyperthyroidism can be caused by____________?
46 - Hyperthyroidism can be caused by____________?
Amiodarone
47 - Hypothyroidism should be treated with daily administration of which of the following thyroid hormone preparations ?
47 - Hypothyroidism should be treated with daily administration of which of the following thyroid hormone preparations ?
Thyroxine (T4)
48 - In children, hypothyroidism causes_____________?
48 - In children, hypothyroidism causes_____________?
Cretinism
49 - In conn's disease, there is an excess of______________?
49 - In conn's disease, there is an excess of______________?
Aldosterone
50 - IN the adrenal gland, androgens are produced by the cells in the____________?
50 - IN the adrenal gland, androgens are produced by the cells in the____________?
Zona reticularis
51 - In thyrotoxicosis , there is______________?
51 - In thyrotoxicosis , there is______________?
Potentiation of catecholamine action
52 - Inhibit b hormone has effect on_______________?
52 - Inhibit b hormone has effect on_______________?
FSH
53 - Insulin facilitates glucose uptake in____________?
53 - Insulin facilitates glucose uptake in____________?
Skeletal muscle
54 - Insulin increases the activity of___________?
54 - Insulin increases the activity of___________?
HMG. CoA reductase
55 - Iodine is primarily important in the biochemical synthesis of______________?
55 - Iodine is primarily important in the biochemical synthesis of______________?
Thyroxine
56 - Low calcium level will cause_____________?
56 - Low calcium level will cause_____________?
All of the above
57 - Menopausal hormonal relations are______________?
57 - Menopausal hormonal relations are______________?
Gonadotropins increase , estrogens decrease
58 - Negative BMR is observed with______________?
58 - Negative BMR is observed with______________?
Thyroid disturbance
59 - Noradrenaline is differentiated from adrenaline by increasing___________?
59 - Noradrenaline is differentiated from adrenaline by increasing___________?
Peripheral resistance
60 - Not a glycoprotein_______________?
60 - Not a glycoprotein_______________?
GH
61 - Not true about T3 and T4 is______________?
61 - Not true about T3 and T4 is______________?
T4 binds to prealbumin
62 - Osteoclasts are inhibited / modified and regulated by____________?
62 - Osteoclasts are inhibited / modified and regulated by____________?
Calcitonin
63 - Ovulation is associated with sudden rise in______________?
63 - Ovulation is associated with sudden rise in______________?
L.H
64 - Oxytocin causes all accept_______________?
64 - Oxytocin causes all accept_______________?
Lactogenesis
65 - Paneth cells secrete which of the following ?
65 - Paneth cells secrete which of the following ?
Antibacterial substance
66 - Posterior pituitary insufficiency leads to______________?
66 - Posterior pituitary insufficiency leads to______________?
Diabetes insipidus
67 - Progesterone production in the ovary is primarily by______________?
67 - Progesterone production in the ovary is primarily by______________?
Corpora lutea
68 - Regarding myxedema the following are true except______________?
68 - Regarding myxedema the following are true except______________?
B.M.R increased by 30 -45%
69 - Removal of parathyroid gland produces the following changes EXCEPT_________________?
69 - Removal of parathyroid gland produces the following changes EXCEPT_________________?
Decrease in plasma phosphate level
70 - Reverse T3 is__________________?
70 - Reverse T3 is__________________?
Isomerisation product of T3 and inactive
71 - Steroid hormones are believed to enter target cells via_______________?
71 - Steroid hormones are believed to enter target cells via_______________?
Simple diffusion
72 - Tetany is characterized by ________________?
72 - Tetany is characterized by ________________?
Hypertonicity of muscles
73 - The blood glucose level in diabetes mellitus is decreased by removal of the______________?
73 - The blood glucose level in diabetes mellitus is decreased by removal of the______________?
Anterior pituitary
74 - The catecholamines secreted by adrenal medulla______________?
74 - The catecholamines secreted by adrenal medulla______________?
Increases the blood glucose level by favoring glycogenolysis in blood and muscle cells
75 - The decreased phosphate level seen in hyper parathyroidism is due to ________________?
75 - The decreased phosphate level seen in hyper parathyroidism is due to ________________?
Decreased renal phosphate absorption
76 - The effect which is seen due to decrease in serum calcium concentration is_______________?
76 - The effect which is seen due to decrease in serum calcium concentration is_______________?
Excitability of the muscle
77 - The following hormones increase the blood glucose level except_____________?
77 - The following hormones increase the blood glucose level except_____________?
Parathormone
78 - The hormone , which stimulates uterus contraction and lets down milk, is_____________?
78 - The hormone , which stimulates uterus contraction and lets down milk, is_____________?
Oxytocin
79 - The hormone having the maximum effect on granulation wound healing is____________?
79 - The hormone having the maximum effect on granulation wound healing is____________?
Cortisone
80 - The hormone whose deficiency causes diabetes insipidus is released from which nucleus of pituitary ________________?
80 - The hormone whose deficiency causes diabetes insipidus is released from which nucleus of pituitary ________________?
Supraoptic
81 - The most significant immediate result of lowered serum calcium is_______________?
81 - The most significant immediate result of lowered serum calcium is_______________?
Decalcification of bones
82 - The primary effect of calcitonin is__________________?
82 - The primary effect of calcitonin is__________________?
Bone deposition
83 - The primary site of action of antidiuretic hormone is on the_______________?
83 - The primary site of action of antidiuretic hormone is on the_______________?
Distal tubules and collecting ducts in the kidney
84 - The receptors for parathyroid hormone are present in______________?
84 - The receptors for parathyroid hormone are present in______________?
Osteoclasts
85 - The supraoptic nucleus of the hypothalamus is believed to control secretion of which of the following hormones ?
85 - The supraoptic nucleus of the hypothalamus is believed to control secretion of which of the following hormones ?
Antidiuretic hormone
86 - There absorption of sodium chloride in kidneys is controlled by the hormones____________?
86 - There absorption of sodium chloride in kidneys is controlled by the hormones____________?
Aldosterone
87 - Thyroxine causes all the following except______________?
87 - Thyroxine causes all the following except______________?
Decreased cell metabolism
88 - Trousseau's sign and chovstek's sings are positive in___________?
88 - Trousseau's sign and chovstek's sings are positive in___________?
Hypoparathyroidism
89 - Vasopressin is synthesized in the_____________?
89 - Vasopressin is synthesized in the_____________?
Hypothalamus
90 - Which amongst the following is the gold standard for demonstrating hcG____________?
90 - Which amongst the following is the gold standard for demonstrating hcG____________?
Radio immune assay
91 - Which hormone , together with the catecholamines enhances the tone of vascular smooth muscle and assists in elevating blood pressure ?
91 - Which hormone , together with the catecholamines enhances the tone of vascular smooth muscle and assists in elevating blood pressure ?
Cortisol
92 - Which hormone does not have corresponding release hormone produced in pituitary ?
92 - Which hormone does not have corresponding release hormone produced in pituitary ?
Prolactin
93 - Which hormone is released when serum calcium decreases ?
93 - Which hormone is released when serum calcium decreases ?
Parathormone
94 - Which is false regarding insulin______________?
94 - Which is false regarding insulin______________?
Glycopeptide
95 - Which of the following anterior pituitary hormones is primarily under inhibitory control of hypothalamus ?
95 - Which of the following anterior pituitary hormones is primarily under inhibitory control of hypothalamus ?
Prolactin
96 - Which of the following hormones act via cAMP ?
96 - Which of the following hormones act via cAMP ?
Parathormone
97 - Which of the following hormones does not affect growth ?
97 - Which of the following hormones does not affect growth ?
Oxytocin
98 - Which of the following hormones exerts the least effect on calcium metabolism of bone tissue ?
98 - Which of the following hormones exerts the least effect on calcium metabolism of bone tissue ?
Nor epinephrine
99 - Which of the following hormones increase the sensitivity of heart to epinephrine________________?
99 - Which of the following hormones increase the sensitivity of heart to epinephrine________________?
Thyroid
100 - Which of the following hormones is released from the posterior pituitary ?
100 - Which of the following hormones is released from the posterior pituitary ?
Antidiuretic hormone
101 - Which of the following is associated with a low concentration of ionized calcium in the serum ?
101 - Which of the following is associated with a low concentration of ionized calcium in the serum ?
Tetany
102 - Which of the following is called hunger hormone______________?
102 - Which of the following is called hunger hormone______________?
Glucagon
103 - Which of the following results due to excessive parathormone secretion_______________?
103 - Which of the following results due to excessive parathormone secretion_______________?
Increased serum calcium
104 - Which of the following statements about the action of the somatomedin is true ?
104 - Which of the following statements about the action of the somatomedin is true ?
They promote growth of bone and cartilage
105 - Which of these following is not an effect of insulin ?
105 - Which of these following is not an effect of insulin ?
Increased glycogenolysis
106 - Which one of the following is a precursor of both gonadal and adrenocortical hormones_____________?
106 - Which one of the following is a precursor of both gonadal and adrenocortical hormones_____________?
Progesterone
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