1 - 1 molelcule of glucose forms _______ molecules of pyruvate?
1 - 1 molelcule of glucose forms _______ molecules of pyruvate?
2
2 - A fatty acid that is not synthesized in man is_____________?
2 - A fatty acid that is not synthesized in man is_____________?
Linoleic acid
3 - Acetyl CoA is produced from which fuel sources_____________?
3 - Acetyl CoA is produced from which fuel sources_____________?
All of the above
4 - Adipose tissue releases free fatty acids in the________________?
4 - Adipose tissue releases free fatty acids in the________________?
Fasting state
5 - Adrenaline acts on which enzyme in glycogenolysis ?
5 - Adrenaline acts on which enzyme in glycogenolysis ?
Phosphorylase
6 - All are derived of cholesterol except________________?
6 - All are derived of cholesterol except________________?
Cholecystokinin
7 - All are true of the genetic code except____________?
7 - All are true of the genetic code except____________?
Punctuation
8 - All are true regarding glucose 6 phosphate deficiency except______________?
8 - All are true regarding glucose 6 phosphate deficiency except______________?
Hyperglycemia
9 - All of the following are substrates for gluconeogenesis except_______________?
9 - All of the following are substrates for gluconeogenesis except_______________?
Oleic acid
10 - All these reactions take place inside the mitochondria except____________?
10 - All these reactions take place inside the mitochondria except____________?
EMP pathway
11 - Ammonia produced by brain is trapped as_____________?
11 - Ammonia produced by brain is trapped as_____________?
Glutamine
12 - An enzyme not involved in glycolysis is______________?
12 - An enzyme not involved in glycolysis is______________?
Glycerophosphate dehydrogenase
13 - An essential for the conversion of glucose to glycogen in liver is____________?
13 - An essential for the conversion of glucose to glycogen in liver is____________?
UTP
14 - Blood glucose level cannot be augmented by mobilization of muscle glycogen due to lack of_____________?
14 - Blood glucose level cannot be augmented by mobilization of muscle glycogen due to lack of_____________?
G-6-P phydrogenase
15 - B-oxidation of odd-chain fatty aids produce_______________?
15 - B-oxidation of odd-chain fatty aids produce_______________?
Propionyl CoA
16 - Cane sugar is____________?
16 - Cane sugar is____________?
Surose
17 - Chargaff rule states that___________?
17 - Chargaff rule states that___________?
A+G=T+C
18 - Codons are present on_____________?
18 - Codons are present on_____________?
m-RNA
19 - Daily requirement of iron in man is_____________?
19 - Daily requirement of iron in man is_____________?
10 mg
20 - Denaturation of double stranded DNA involves_______________?
20 - Denaturation of double stranded DNA involves_______________?
It becomes single stranded reversibly
21 - Dietary fibre is rich in_____________?
21 - Dietary fibre is rich in_____________?
Cellulose
22 - DNA double helix is bound by_____________?
22 - DNA double helix is bound by_____________?
Hydrogen bond
23 - During conversion of glycerol to pyruvic acid, the first glycolytic intermediate to form is_______________?
23 - During conversion of glycerol to pyruvic acid, the first glycolytic intermediate to form is_______________?
Dihydroxy acetone phosphate
24 - End product of purine metabolism is______________?
24 - End product of purine metabolism is______________?
Uric acid
25 - Endogenous triglycerides in plasma is maximally bound to________________?
25 - Endogenous triglycerides in plasma is maximally bound to________________?
VLDL
26 - Enzymes concerned with the citric acid cycle are found in the____________?
26 - Enzymes concerned with the citric acid cycle are found in the____________?
Mitochondria
27 - Enzymes increase reaction rates by______________?
27 - Enzymes increase reaction rates by______________?
Decreasing the energy of activation
28 - Examples of monounsaturted fatty acids are______________?
28 - Examples of monounsaturted fatty acids are______________?
Oleic acid
29 - Fat provides ______% of body's calories?
29 - Fat provides ______% of body's calories?
0.3
30 - Fatty acid oxidation occurs in______________?
30 - Fatty acid oxidation occurs in______________?
Mitochondria
31 - Fatty aids help in synthesis of all except____________?
31 - Fatty aids help in synthesis of all except____________?
Glucose
32 - Ferritin – an inactive form of iron is stored in_____________?
32 - Ferritin – an inactive form of iron is stored in_____________?
Liver
33 - Fructose intolerance is to_____________?
33 - Fructose intolerance is to_____________?
Fructose and sucrose
34 - Galactosemia commonly is due to deficiency of_____________?
34 - Galactosemia commonly is due to deficiency of_____________?
Galactose 1 phosphatase uridyl transferase
35 - Genes are_____________?
35 - Genes are_____________?
Deoxy ribonucleic acid
36 - Gluconeogenesis occurs in the liver and _______?
36 - Gluconeogenesis occurs in the liver and _______?
Kidney
37 - Glucose 6 phosphatase deficiency is seen in______________?
37 - Glucose 6 phosphatase deficiency is seen in______________?
Von Gierke's disease
38 - Glucose can be synthesized from all except_____________?
38 - Glucose can be synthesized from all except_____________?
Acetoacetate
39 - Glycogen breakdown leads to formation of______________?
39 - Glycogen breakdown leads to formation of______________?
Glucose & Lactic acid
40 - Glycogen synthesis is increased by_____________?
40 - Glycogen synthesis is increased by_____________?
Insulin
41 - High content of cholesterol is present in_______________?
41 - High content of cholesterol is present in_______________?
Egg yolk
42 - Highest binding of iron in plasma is seen with___________?
42 - Highest binding of iron in plasma is seen with___________?
Transferrin
43 - HMG CoA reductase is inhibited by_____________?
43 - HMG CoA reductase is inhibited by_____________?
Lovastatin
44 - HMG-CoA is formed during metabolism of all except______________?
44 - HMG-CoA is formed during metabolism of all except______________?
Bile acids
45 - HMP shunt is of great importance in cellular metabolism because its produces_____________?
45 - HMP shunt is of great importance in cellular metabolism because its produces_____________?
NADPH
46 - In all the following RNA participates directly except________________?
46 - In all the following RNA participates directly except________________?
Post translation modification
47 - In glycolysis ATP is produced by the following enzyme______________?
47 - In glycolysis ATP is produced by the following enzyme______________?
Phosphoglycerate kinase
48 - In human body which of the following trace element is next to iron_______________?
48 - In human body which of the following trace element is next to iron_______________?
Zn++
49 - In molecular cloning, Blue White screening is used for_______________?
49 - In molecular cloning, Blue White screening is used for_______________?
To identify desired chromosomal DNA insert in plasmid vectors
50 - In Niemann-Pick's disease the following substrance accumulate in CNS in excess______________?
50 - In Niemann-Pick's disease the following substrance accumulate in CNS in excess______________?
Phosphosphingosides
51 - In prolonged starvation the main nergy source of brain is_____________?
51 - In prolonged starvation the main nergy source of brain is_____________?
Ketone bodies
52 - In TCA cycle or tricarboxylic acid cycle, which is first formed________________?
52 - In TCA cycle or tricarboxylic acid cycle, which is first formed________________?
Citrate
53 - In TCA cycle substrate level phosphorylation occurs at____________?
53 - In TCA cycle substrate level phosphorylation occurs at____________?
Thiokinase
54 - In TCA cycle, citrate is converted in to after losing a molecule of H2O_____________?
54 - In TCA cycle, citrate is converted in to after losing a molecule of H2O_____________?
Cisaconitate
55 - In TCA, substrate level phospherylation takes place in______________?
55 - In TCA, substrate level phospherylation takes place in______________?
Succinyl CoA to Succinate
56 - In which type of glycogen storage disease is hyper uricemia a feature ?
56 - In which type of glycogen storage disease is hyper uricemia a feature ?
I
57 - Increase in lactate and pyruvate is seen in deficiency of_____________?
57 - Increase in lactate and pyruvate is seen in deficiency of_____________?
Thiamine
58 - Increase in pyruvate and lactate is seen in which of the following deficiency ?
58 - Increase in pyruvate and lactate is seen in which of the following deficiency ?
Thiamine
59 - Inhibition of glycolysis by O2 is known a_____________?
59 - Inhibition of glycolysis by O2 is known a_____________?
Pasteur effect
60 - Inside the cell, the substance, which contributes to most of the osmolality, is________________?
60 - Inside the cell, the substance, which contributes to most of the osmolality, is________________?
Potassium
61 - Insulin acts on which enzyme in glycolysis ?
61 - Insulin acts on which enzyme in glycolysis ?
Glucokinase
62 - Insulin caused lipogenesis by all except____________?
62 - Insulin caused lipogenesis by all except____________?
Inhibits Pyruvate dehydrogenase
63 - Insulin increase the following pathways in liver EXCEPT____________?
63 - Insulin increase the following pathways in liver EXCEPT____________?
Glucose synthesis
64 - Iron absorption is decreased in presence of all except____________?
64 - Iron absorption is decreased in presence of all except____________?
Ascorbic acid
65 - Ketone bodies are by products of metabolism of_____________?
65 - Ketone bodies are by products of metabolism of_____________?
Fat
66 - Ketone bodies are normally synthesized from______________?
66 - Ketone bodies are normally synthesized from______________?
Acetyl-CoA
67 - Ketone body formation takes place in_______________?
67 - Ketone body formation takes place in_______________?
Liver
68 - Kinase requires_______________?
68 - Kinase requires_______________?
Mg++
69 - Kreb's cycle does not occur in______________?
69 - Kreb's cycle does not occur in______________?
RBC
70 - Kreb's cycle occurs in _________ conditions?
70 - Kreb's cycle occurs in _________ conditions?
Aerobic
71 - Limiting factory for fatty acid synthesis_________________?
71 - Limiting factory for fatty acid synthesis_________________?
Acetyl CoA carboxylase
72 - Lipid from tissue is carried to liver by_____________?
72 - Lipid from tissue is carried to liver by_____________?
HDL
73 - Lipid is required in the average diet because it________________?
73 - Lipid is required in the average diet because it________________?
Provides essential fatty acid
74 - Major contribution towards gluconeogenesis is by____________?
74 - Major contribution towards gluconeogenesis is by____________?
Lactate
75 - McArdles disease is due to the deficiency of_____________?
75 - McArdles disease is due to the deficiency of_____________?
Myophosphorylase
76 - Most lipogenic____________?
76 - Most lipogenic____________?
Fructose
77 - Mutations are due to changes in_________________?
77 - Mutations are due to changes in_________________?
DNA nucleotide sequence
78 - NADPH is generated by the action of____________?
78 - NADPH is generated by the action of____________?
Glucose 6 phosphate dehydrogenase
79 - NADPH is required for________________?
79 - NADPH is required for________________?
Fatty acid synthesis
80 - Nonsense codons bring about__________________?
80 - Nonsense codons bring about__________________?
Termination of protein synthesis
81 - Normal level of serum phosphorous is_____________?
81 - Normal level of serum phosphorous is_____________?
2.5 – 4.5 mgm%
82 - Normal serum calcium level is_______________?
82 - Normal serum calcium level is_______________?
9-11 mg/dl
83 - Number of ATP molecules generated in the conversion of glycogen of lactate is_____________?
83 - Number of ATP molecules generated in the conversion of glycogen of lactate is_____________?
2
84 - On complete hydrolysis of DNA we will get all the following except______________?
84 - On complete hydrolysis of DNA we will get all the following except______________?
Adenosine
85 - One molecule of acetyl Co-A gives rise to ________ ATP molecules?
85 - One molecule of acetyl Co-A gives rise to ________ ATP molecules?
12
86 - Peroxidase enzyme contain______________?
86 - Peroxidase enzyme contain______________?
Selenium
87 - Phosphofructokinase is the key enzyme of______________?
87 - Phosphofructokinase is the key enzyme of______________?
Glycolysis
88 - Prostaglandin synthesis is partially switched off by______________?
88 - Prostaglandin synthesis is partially switched off by______________?
Cyclo-oxygenase inhibition
89 - Rate limiting step in cholesterol synthesis is_______________?
89 - Rate limiting step in cholesterol synthesis is_______________?
HMG CoA reductase
90 - Renal threshold for glucose is______________?
90 - Renal threshold for glucose is______________?
180 mg/ dl
91 - Restriction endonuclease cleaves______________?
91 - Restriction endonuclease cleaves______________?
Double stranded DNA
92 - R-RNA is mainly produced mainly in___________?
92 - R-RNA is mainly produced mainly in___________?
Nucleolus
93 - Saponification means hydrolysis of fats by________________?
93 - Saponification means hydrolysis of fats by________________?
Alkali
94 - Serum creatine kinase-3 (CK-3) is elevated in_______________?
94 - Serum creatine kinase-3 (CK-3) is elevated in_______________?
Muscular dystrophy
95 - Sites where HMP shunts can occur include_______________?
95 - Sites where HMP shunts can occur include_______________?
All of the above
96 - Step in HMP pathway requiring TPP_____________?
96 - Step in HMP pathway requiring TPP_____________?
Transketolase
97 - The citric acid cycle is the final pathway for oxidation of______________?
97 - The citric acid cycle is the final pathway for oxidation of______________?
None of the above
98 - The compound that can give rise to glucose by gluconeogenesis is_____________?
98 - The compound that can give rise to glucose by gluconeogenesis is_____________?
Lactate
99 - The conversion of glucose 6-P to fructose 6-P is an example of which of the following reactions___________?
99 - The conversion of glucose 6-P to fructose 6-P is an example of which of the following reactions___________?
Isomerisation
100 - The end product of glycolysis under anaerobic conditions is_______________?
100 - The end product of glycolysis under anaerobic conditions is_______________?
Lactic acid
101 - The enzyme involved in the first committed step of glycolysis is____________?
101 - The enzyme involved in the first committed step of glycolysis is____________?
Hexokinase
102 - The first product of glycogenolysis is_____________?
102 - The first product of glycogenolysis is_____________?
Glucose 1- phosphatase
103 - The following is not a phospholipid______________?
103 - The following is not a phospholipid______________?
Cerebroside
104 - The human plasma lipoprotein containing the highest percentage of triacylglycerol by weight is______________?
104 - The human plasma lipoprotein containing the highest percentage of triacylglycerol by weight is______________?
Chylomicrons
105 - The initiation codon for protein synthesis is_____________?
105 - The initiation codon for protein synthesis is_____________?
AUG
106 - The ketone bodies, which are excreted in diabetic ketoacidosis ?
106 - The ketone bodies, which are excreted in diabetic ketoacidosis ?
Acetoacetic acid and beta hydroxyl butyric acid
107 - The key enzyme of gluconeogenesis is______________?
107 - The key enzyme of gluconeogenesis is______________?
Pyruvate carboxylase
108 - The lipid, which acumulates in fatty liver, is_______________?
108 - The lipid, which acumulates in fatty liver, is_______________?
Triglycerides
109 - The lipoprotein particles that have the highest percentage concentration of cholesterol is_______________?
109 - The lipoprotein particles that have the highest percentage concentration of cholesterol is_______________?
LDL (Low density lipoprotein)
110 - The main enzyme responsible for activation of xenobiotics in (detoxification)____________?
110 - The main enzyme responsible for activation of xenobiotics in (detoxification)____________?
Cytochrome P-450
111 - The main function of HDL is____________?
111 - The main function of HDL is____________?
None of the above
112 - The main pathway for De – Novo synthesis of fatty acids occurs in_______________?
112 - The main pathway for De – Novo synthesis of fatty acids occurs in_______________?
Cytosol
113 - The main pathways of metabolism in brain are______________?
113 - The main pathways of metabolism in brain are______________?
Glycolysis and citric acid cycle
114 - The major lipids that make up the cell membrane are_______________?
114 - The major lipids that make up the cell membrane are_______________?
Phospholipids
115 - The monsaccharide glucose is best described by which one of the following statements ?
115 - The monsaccharide glucose is best described by which one of the following statements ?
It formspart of the disaccharide sucrose
116 - The most important role of cholesterol is_____________?
116 - The most important role of cholesterol is_____________?
It is a component of cell membrane
117 - The normal level of serum cholesterol is_______________?
117 - The normal level of serum cholesterol is_______________?
150-250 mgs/100 ml
118 - The normal value of serum potassium level is____________?
118 - The normal value of serum potassium level is____________?
3.8-5 meq/L
119 - The patient suffered from hypogondism, failure to thrive, lose of taste and unable to maintain stability. This shows the deficiency of_____________?
119 - The patient suffered from hypogondism, failure to thrive, lose of taste and unable to maintain stability. This shows the deficiency of_____________?
Zinc
120 - The portion of DNA in Which RNA polymerase binds and starts transcription is called______________?
120 - The portion of DNA in Which RNA polymerase binds and starts transcription is called______________?
Promoter region
121 - The precursor of cholesterol synthesis is________________?
121 - The precursor of cholesterol synthesis is________________?
Acetyl CoA
122 - The precursor of steroid is_______________?
122 - The precursor of steroid is_______________?
Cholesterol
123 - The product of oxidation of odd chainfatty acids is______________?
123 - The product of oxidation of odd chainfatty acids is______________?
Propionyl CoA
124 - The rate of absorption of sugars by the small intestine is highest for_______________?
124 - The rate of absorption of sugars by the small intestine is highest for_______________?
Hexoses
125 - The reducing equivalent for fatty acid synthesis is derived form____________?
125 - The reducing equivalent for fatty acid synthesis is derived form____________?
Pentose phosphate pathway
126 - The sigma subunit of prokaryotic RNA polymerase_______________?
126 - The sigma subunit of prokaryotic RNA polymerase_______________?
Specifically recognizes the promoter site
127 - The substance essential for transfter of fatty acids across mitochondrial membrance_____________?
127 - The substance essential for transfter of fatty acids across mitochondrial membrance_____________?
Carnitine
128 - The sugar component of cerebrosides is_____________?
128 - The sugar component of cerebrosides is_____________?
Galactose
129 - The tissue with the highest glycogen content (mg/100gm)_____________?
129 - The tissue with the highest glycogen content (mg/100gm)_____________?
Liver
130 - The total blood concentration of ketone bodies in well fed individual is__________?
130 - The total blood concentration of ketone bodies in well fed individual is__________?
1 mg%
131 - The uptake of glucose by the liver increase following a carbohydrate meal because____________?
131 - The uptake of glucose by the liver increase following a carbohydrate meal because____________?
There is increase in phosphorylation of glucose by glucokinase
132 - Transcription is the synthesis of____________?
132 - Transcription is the synthesis of____________?
Single stranded complimentary copy of DNA
133 - Translation occurs at______________?
133 - Translation occurs at______________?
Ribosome
134 - Triglyceride synthesis synthesis is increased by______________?
134 - Triglyceride synthesis synthesis is increased by______________?
Insulin
135 - Triglycerides in serum are transported by_______________?
135 - Triglycerides in serum are transported by_______________?
LDL
136 - True about prostaglandins is______________?
136 - True about prostaglandins is______________?
All are true
137 - Type II glycogen storage disorder is due to deficiency of______________?
137 - Type II glycogen storage disorder is due to deficiency of______________?
Alpha -Glucosidase
138 - Unsaturated fatty acids are converted to______________?
138 - Unsaturated fatty acids are converted to______________?
Prostaglandins
139 - Unwinding of DNA is done by____________?
139 - Unwinding of DNA is done by____________?
Topo isomerase
140 - What high energy phosphate compound is formed in the citric acid cycle through substrate level phosphorylation______________?
140 - What high energy phosphate compound is formed in the citric acid cycle through substrate level phosphorylation______________?
GTP
141 - Which acid is formed in the citric acid cycle ?
141 - Which acid is formed in the citric acid cycle ?
Oxaloacetic acid
142 - Which base is not found in DNA________________?
142 - Which base is not found in DNA________________?
Uracil
143 - Which is not a oligosaccharide sugar ?
143 - Which is not a oligosaccharide sugar ?
Galactose
144 - Which is not seen in HMG CoA pathway ?
144 - Which is not seen in HMG CoA pathway ?
Pyruvate
145 - Which metabolite of TCA cycle is used in detoxification of ammonia in brain_____________?
145 - Which metabolite of TCA cycle is used in detoxification of ammonia in brain_____________?
Alpha ketoglutarate
146 - Which of the following enzymes use NADP as coenzyme ________________?
146 - Which of the following enzymes use NADP as coenzyme ________________?
Glucose 6-Phosphate dehydrogenase
147 - Which of the following fatty acids are not syntehsised in human body_____________?
147 - Which of the following fatty acids are not syntehsised in human body_____________?
Arachidonic, linolenic and linoleic acid
148 - Which of the following is a non-reducing sugar____________?
148 - Which of the following is a non-reducing sugar____________?
Sucrose
149 - Which of the following is a phospholipid________________?
149 - Which of the following is a phospholipid________________?
Sphingomyelin
150 - Which of the following is abnormal constituent of urine_____________?
150 - Which of the following is abnormal constituent of urine_____________?
glucose
151 - Which of the following is correctly matched ?
151 - Which of the following is correctly matched ?
Succinyl CoA to succinate -1 ATP is formed
152 - Which of the following is most important content of diet ?
152 - Which of the following is most important content of diet ?
Minerals
153 - Which of the following is not a ketone body______________?
153 - Which of the following is not a ketone body______________?
Acetic acid
154 - Which of the following is not a polymer of glucose?
154 - Which of the following is not a polymer of glucose?
Inulin
155 - Which of the following is not a product of HMP shunt_____________?
155 - Which of the following is not a product of HMP shunt_____________?
D sedoheptulose 5 phosphate
156 - Which of the following is used in recombinant DNA technology ?
156 - Which of the following is used in recombinant DNA technology ?
Restriction endonucleases
157 - Which of the following organs cannot use ketone bodies_______________?
157 - Which of the following organs cannot use ketone bodies_______________?
Liver
158 - Which of the following process in involved in conversion of DNA to RNA___________?
158 - Which of the following process in involved in conversion of DNA to RNA___________?
Transcription
159 - Which of the following statement is TRUE? The hydrolysis of lactose yields glucose and galactose_____________?
159 - Which of the following statement is TRUE? The hydrolysis of lactose yields glucose and galactose_____________?
The hydrolysis of lactose yields glucose and galactose
160 - Which of them is multienzyme complex_____________?
160 - Which of them is multienzyme complex_____________?
Both A & B
161 - Which one of the following enzymes provides a link between glycolysis and the citric acid cycle ?
161 - Which one of the following enzymes provides a link between glycolysis and the citric acid cycle ?
Pyruvate dehydrogenase
162 - Which one of the following is a monosaccharide______________?
162 - Which one of the following is a monosaccharide______________?
Fructose
163 - Which one of the following is the correct sequential order in which the given enzymes of kreb's cycle are formed after a molecule of acetyl CoA______________?
163 - Which one of the following is the correct sequential order in which the given enzymes of kreb's cycle are formed after a molecule of acetyl CoA______________?
Citrate, Oxalocetate, Ketoglutarate
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