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Genetics Most Important MCQs: Set#. 2

201 - Contractile protein/proteins






Both a and b

202 - CRISPR RNA's one end binds to CRISPR- Cas nuclease and other bind to






Gene of interest

203 - CRISPR-Cas is used to modify






Gene

204 - Cultivated autopolyploids of wheat






Both a and b

205 - Darwin's theory of evolution was criticised due to lack of






Genetic basis of variation

206 - Data from human genome project indicate that the X chromosome has at least___________genes






900

207 - Data from human genome project indicate that the y chromosome has at least___________genes






75

208 - Deep red color of urine is symptom of






Porphyria variegata

209 - Defective mitochondria play a role in _________






Aging

210 - Diamond-Blackfan anemia is a rare,dominant disorder characterized by________malfunction






Bone marrow

211 - Digestion of chromatin by certain endonucleases, yields DNA fragments that are about _____ base pairs in length or multiples thereof






200

212 - Diploid bananas contain hard _________






Seeds

213 - Discontinuous DNA synthesis was fierst presented by






Okazaki

214 - Division of cytoplasm is called






Cytokinesis

215 - Division of nucleus is called






Karyokinesis

216 - DNA and RNA absorb UV light most strongly at






260 nm

217 - DNA as atransforming agent was proved by






Avery

218 - DNA as heredity material was experimentall proved by_________and cowoerkers in 1944






Avery

219 - DNA as heredity material was proved by experiments in_______






1944

220 - DNA associated proteins, histones are___________charged






Positively

221 - DNA associated proteins, nonhistones are___________charged






Less Positively

222 - DNA binding protein in bacteria






Both a and b

223 - DNA helicase in bacteria is made up of multiple copies of_____________






DnaB

224 - DNA is found in






All of these

225 - DNA polymeraseIII requires _________ to start DNA synthesis






Primer

226 - DNA serves as the genetic material in all living organisms on earth except some __________






Viruses

227 - DNA was first studied in 1869 by a Swiss chemist______






Miescher

228 - DNA__________is found exclusively in mitochondria






Polymerase gamma

229 - Domestication of animals started between_______B.C






8000 to 1000

230 - Double helix structure of DNA was proposed by






Watson

231 - Down syndrome in human is example of






Trisomy

232 - Down syndrome in human occur 1 in every________births






800

233 - Down syndrome is not






Inherited

234 - Duchene muscular dystrophy in human is ________trait






X-linked

235 - Duchene muscular dystrophy in human is often fatal in the early






20s

236 - Duchenne muscular dystrophy (DMD) can be cured by






Exon skipping

237 - During complete linkage only______________gametes are produced






Both a and b

238 - During _______________ the centromere are positioned on the equatorial plate






MetaphaseII

239 - During Bacteriophage life cycle about_______viruses are constructed in one cycle






200

240 - During conjugation, _________of plasmids of donor bactreium is transferred to recipient bacterium






Single strand

241 - During elongation of translation, _________binds GTP, brings aminoacyl tRNA to the A site of the ribosome






EF-Tu

242 - During elongation of translation,___________ regulate EF-Tu activity






EF-Ts

243 - During elongation of translation,___________ stimulates translocation; GTP dependent






EF-G

244 - During gamete formation loop formation occurs between homologous chromosomes having






All of these

245 - During Garrod time's, ___________was/were used in place of genes






Both a and b

246 - During initiation of translation,_______ binds to 30 S subunit and preventing it from associating with the 50S subunit prematurely






IF3

247 - During initiation of translation,________ binds to the initiator fMet-tRNA and transfer it to the P site of the 30S-mRNA complex






IF2

248 - During initiation of translation,__________ binds to 30 S subunit and prevent aminacyl tRNA from binding to the A site prematurely






IF1

249 - During meoisis, a____________ number of cross over events occur in each tetrad






limited

250 - During mitosis nuclear membrane disappears in






prophase

251 - During mitosis the condensation of chromosomes occurs in






prophase

252 - During mitosis the splitting of sister chromatids occurs in






prophase

253 - During mixed infection of mutant phages, the production of wild type phage is called






Complementation

254 - During modification of RNA transcripts in eukaryotes, the__________are spliced






Introns

255 - During posttranslational modification of proteins , trimming in polypeptide chain occur in____________






Insulin

256 - During posttranslational modification of proteins the_______residue isremoved enzymatically in bacteria






Formylmethionine

257 - During posttranslational modification of proteins, addition of __________may occur






Both a and b

258 - During prophase II each dyad is composed of ______pair/pairs of sister chromateds attached with common centromeric region






1

259 - During synkaryon, most of the chromosomes of one nucleus are gradually






Lost

260 - During termination of translation,___________ behave like RF1; specific for UGA and UAA






RF2

261 - During termination of translation,___________ catalyses release of the polypeptide chain from tRNA and dissociation of the translocation complex






RF1

262 - During termination of translation,___________ stimulates other releasing factors






RF3

263 - During the first________minutes, no genetic recombination is detected in bacterial conjugation






8

264 - During_________each daughter cell receive equal amount of cytoplasm






Spermatogenesis

265 - During_________each daughter cell receive unequal amount of cytoplasm






Oogenesis

266 - Dystrophin gene contain ________kb






2400

267 - Each chromosome become monad in






TelophaseII

268 - Each chromosome contains a constricted region called






Centromere

269 - Each complete turn of the DNA double helix contains__________bases






10

270 - Each complete turn of the DNA double helix is_________angstrom






34

271 - Each diploid organism contains two copies of each gene as consequence of






Biparental inheritance

272 - Each micronucleoli of oocyte is equivalent to






NOR(Nuclear organizer region)

273 - Each nucleosome consists of about __________base pairs of DNA wraped around eight histone protein molecules






200

274 - Each nucleosome measures about_________nm at its longest point






11

275 - Each polypeptide has amino group at one end and __________at the other end






Carboxyl group

276 - Each polytene chromosome is ___________µm long






200-600

277 - Each strain of Diplococcus may be one of dozens different types of _________






Serotypes

278 - Each strain of Diplococcus may be one of______different types of serotypes






Dozens

279 - Each synapsed pair of homologs is intially called






Bivalent

280 - Each word within mRNA consists of _________ribonucleotide letters






3

281 - Edwards is ____________trisomy






47,18

282 - Electrophoretic separation of nucleic acids is at heart of a variety of other techniques such as






Both a and b

283 - Endosymbionts theory was proposed by






Margulis

284 - Enlarge breast and rounded hips are characters of






Klinefelter syndrome

285 - Envieonmental factor/factors which can modify gene expression






All of these

286 - Epicanthic fold in each eye is characteristic of






Down syndrome

287 - Episomes are __________ which can integrate with bacterial chromosome






Plasmids

288 - Eukaryotes chromosome contains________replication origin/origins






Multiple

289 - Evening promose produces ________ flowers when grown at 18áµ’C






White

290 - Evening promose produces ________ flowers when grown at 23áµ’C






Red

291 - Example of Robertsonian translocation






Down syndrome

292 - except for_________,each member of human species exhibits a distinctve set of traits






Identical twins

293 - ExPASy(Expert Protein Analysis System) was hosted by the _______Institute of Bioinformatics






Swiss

294 - Exponential growth rate of bacteria






log phase

295 - Extranuclear inheretance is also known as






All of these

296 - F- bacteria are






Recipient

297 - F factor in bacteria contains about___________genes






40

298 - F factor consists of a circular, double stranded _______






DNA

299 - F factor in bacteria contains about___________nucleotide pairs






100000

300 - F factor is about_________ of the bacterial chromosome






2

301 - F+ bacteria are






Donor

302 - Fertility factor(F factor) is found in_____________bacteria






F+

303 - Fewer than______percent of the progeny of parents heterozygous for a reciprocal translocation survive






50

304 - First x-chromosome was identified in the somatic cells of female butterfly Protenor by






Edmund B.Wilson

305 - For gene mapping, crossing over is necessary in Eukaryotes and ____________in Bacteria






All of these

306 - For successful cross, the genotype of the organism must be_________at all loci






Heterozygous

307 - For the insertion of gene of interest into carrier DNA molecules called






Vector

308 - Found in connective tissues






Collagen

309 - Found in hair of orhanisms






Keratin

310 - GC rich hairpin secondary structure is immediately followed by a string of ________residues






Uracil

311 - GC rich Hairpin secondary structure is stable with _______rich nucleotides






GC

312 - GenBank contains more than_______billon base pairs of sequence data






220

313 - Gene activity is correlated ______________of histones






All of these

314 - Gene redundancy or gene amplification in oocytes is needed to constuct_________






Ribosome

315 - Genes expression___________with increase in ploidy






Both a and b

316 - Genes which are present on both X and Y chromosomes are called_______________genes






Pseudoautosomal

317 - Genetic code is






All of these

318 - Genetic markers are___________portions of specific chromosome






identifiable

319 - Genetics problems are solved by






Punnett square

320 - Giant lampbrush chromosomes are _____________ chromosomes






Meiotic

321 - Giant lampbrush chromosomes are often extended to lengths of __________µm






500-800

322 - Giant lampbrush chromosomes were first observed by






Flemming

323 - Giant polytene chromosomes are found in various tissue/tissues such as_______________in the larvae of some flies






All of these

324 - Giant polytene chromosomes are found in various tissues of in the






All of these

325 - Giant polytene chromosomes were observed by






Balbiani

326 - Giant size chromosomes






Both a and b

327 - Gonadal ridges arises by the _________week of gestation in human






5

328 - G-rich single stranded tails are capable of interacting with upstream sequences within the tail, creating a loop called






t-loop

329 - Group II introns are found in






All of these

330 - GU dinucleotide sequence of snRNAs also called as






Splice donor

331 - Guanine forms_______hydrogen bond with cytosine






3

332 - H substance is present in blood group






All of these

333 - H1 histone proteins are _____________rich






Lysine

334 - H2A histone proteins are _____________rich






Slightly Lysine

335 - H2B histone proteins are _____________rich






Slightly Lysine

336 - H3 histone proteins are _____________rich






Arginine

337 - H4 histone proteins are _____________rich






Arginine

338 - Hairpin secondary structure is formed at the __________of transcription






End

339 - Har Gobind Khorana used______________to synthesize artificial RNA






RNA copolymers

340 - Hemophilia A and B in human are ________traits






X-linked

341 - Hemophilia A gene is located on________chromosome






X

342 - Hershey and Chase to prove that DNA is heridity material worked with






Viruses

343 - Hershey and Chase used___________to prove that DNA is heredity material






Bacteriophage

344 - Heterochromosome in sperm of gross hopper was identified by






McClung

345 - High temperature in ___________ZZ (Pogona vitticeps) can cause sex reversal






Male

346 - Highly repetitive and moderately repetitive DNA of human genome comprise about___________percent






50

347 - Histones contain positively charged amino acid/acids






Both a and b

348 - Historically, the term amber was used to distinguish mutations producing termination codons






UAG

349 - Historically, the term ochre was used to distinguish mutations producing termination codons






UAA

350 - Historically, the term opal was used to distinguish mutations producing termination codons






UGA

351 - Homozygous recessive yellow coat colored mice die_________






Before birth

352 - Horizontal gene tranfer is applied between the member of _____________ species






Both a and b

353 - Horn formation in certain breeds of sheep is_______________trait






Sex influenced inheretance

354 - Host range(h)strain of viruses were discovered by






Salvador Luria

355 - How many types of mapping are commonly used






2

356 - How much Barr body will arise in 47, XXX females






2

357 - How much Barr body will arise in 48, XXXX females






3

358 - How much Barr body will arise in Klinefelter 47, XXY






1

359 - How much Barr body will arise in Turner 45, X females






0

360 - Human mitochondria contain only_________tRNA species






22

361 - Human mtDNA has_______ essential genes






37

362 - Human sex chromosomes were identified by






Joe Hin Tjio

363 - Human sex chromosomes were identified by Joe Hin Tjio in____________






1956

364 - Human traits are studies through






Pedigree

365 - Hyperchromic shift in DNA is Characterized by






All of these

366 - ÃŽ²-globin chain of hemoglobin contains_______ amino acids






146

367 - Identification of gene locus and distance between genes is called






Gene linkage

368 - If differentially staining pattern is produced along mitotic chromosomes is called






G-banding

369 - If 13 percent of flies within mutant genotype show the wild type appearance, the penetrance of mutant genotype will be






87

370 - If a genome has multiple copies of different set of chromosomes






Allopolyploidy

371 - If a genome has multiple copies of same set of chromosomes






Autopolyploidy

372 - If A represent haploid set of chromosome, AAAAAA will be






Hexaploid

373 - If centromere is located at the end of chromosome______is called






Telocentric

374 - If centromere is located close to end of chromosome______is called






Acrocentric

375 - If centromere is located in the middle of chromosome______is called






Metacentric

376 - If centromere is located near the middle of chromosome______is called






Submetacentric

377 - If DNA is subjected to heat






All of these

378 - If fewer DCOs than expected occur, interference will be






Possitive

379 - If more DCOs than expected occur, interference will be






Negative

380 - If only centromeric regions of mitotic chromosomes took up the stain is called






C-banding

381 - If only one member of a homologous pair of chromosomes has an inverted segment






Inversion heterozygote

382 - If petite mutant is crossed with wild type Sacharomyces cervisiae and progeny is petite type and wild type, the petite is__________






Segregational petite

383 - If petite mutant is crossed with wild type Sacharomyces cervisiae and progeny is petite type, the petite is__________






Suppressive petite

384 - If petite mutant is crossed with wild type Sacharomyces cervisiae and progeny is wild type, the petite is__________






Neutral petite

385 - If the centromere is a part of inverted segment






Pericentric inversion

386 - If the centromere is not a part of inverted segment






Paracentric inversion

387 - If the coefficient of coincidence is 0.804 what wil be the interference






0.196

388 - If the dilution factor is to low, the plaques will be






Plentiful

389 - If the eggs of male ZZ (Pogona vitticeps), when incubated in elevated temperature, these egg will produce






Female

390 - If there is no Guanine base in DNA double helix, the helix will forms






Both a and b

391 - If X chromosome and autosome ratio is equal to 0.5, the sex of fruit fly will be






Male

392 - If X chromosome and autosome ratio is equal to one, the sex of fruit fly will be






Female

393 - IIIS type of Diplococcus pneumoniae have characyeristic/s






All of these

394 - IIR type of Diplococcus pneumoniae have characyeristic/s






All of these

395 - In _________, the affected individuals have female external genitalia and internal ducts but have rudimentary ovaries






Turner syndrome

396 - In __________nuclear membrane reformed






Telophase1

397 - In 1927_______worked on virulent and avirulent strains of Diplococcus pneumoniae






Griffith

398 - In 1950, Cavalli-Sforza mutated E.coli K12 with nitrogen mustard into






Hfr

399 - In 1965, inosinic acid (I) was discovered by






Robert Holley

400 - In 1978,_________ reported the presence of telomere






Blackman

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