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Genetics Most Important MCQs: Set#. 3

401 - In a cross between two T2 phages(hr+ x h+r), Which one is recombinant among the following progeny






hr

402 - In a cross between two T2 phages(hr+ x h+r), Which one is/are recombinant among the following progeny






Both b and c

403 - In a species such as E.coli, elongation proceeds at a rate of _________amino acids per second at 37áµ’C






15

404 - In abnormal human hemoglobin (Hb Bethesda), normal Try is substituted with__________ÃŽ²-145






His

405 - In abnormal human hemoglobin (Hb Mexico), normal Gln is substituted with__________ÃŽ±-54






Glu

406 - In abnormal human hemoglobin (Hb Saskatoon), normal His is substituted with__________ÃŽ²-63






Tyr

407 - In abnormal human hemoglobin (Hb Sydney), normal Val is substituted with__________ÃŽ²-67






Ala

408 - In abnormal human hemoglobin (Hb Toronto), normal Ala is substituted with__________ÃŽ±-5






Asp

409 - In abnormal human hemoglobin (HbJ Oxford), normal Gly is substituted with__________ÃŽ±-15






Asp

410 - In ABO blood group system, there are _____________different allele/alleles






3

411 - In all crocodiles, most turtle and some lizards, the sex determination is






TSD(Temerature dependent sex determination)

412 - In an experiment performed by Wollman and Jacob, after 10 minutes of bacterial conjugation, which gene got entry into recipient bacterium






azi

413 - In an experiment performed by Wollman and Jacob, after 15 minutes of bacterial conjugation, which gene got entry into recipient bacterium






ton

414 - In an experiment performed by Wollman and Jacob, after 20 minutes of bacterial conjugation, which gene got entry into recipient bacterium






lac

415 - In an experiment performed by Wollman and Jacob, after 25 minutes of bacterial conjugation, which gene got entry into recipient bacterium






gal

416 - In bacteria each Okazaki fragment contain about__________nucleotides






1000-2000

417 - In bacteria primer is replaced by






DNA polymeraseI

418 - In bacteria proofreading is function of






DNA Polymerase III

419 - In bacteria the monosome is a___________particle






70S

420 - In bacteria, genetic mapping is also called






Both a and b

421 - In bacteria, there is/are ___________releasing factor/factors






3

422 - In bacteria,the sequence of nucleotides AGGAGG on mRNA is called






Shine-Dalgarno sequence

423 - In birds, female is






Hetreogametic

424 - In birds, male is






Homogametic

425 - In boas and pythons, the sex chromosomes composition is






None of these

426 - In Caenorrhabditis elegans male is






X0

427 - In Caenorrhabditis elegans, if the ratio of X:A is 0.5, the sex will be






Male

428 - In Caenorrhabditis elegans, if the ratio of X:A is 1, the sex will be






Hermaphrodite

429 - In Caenorrhabditis elegans, normally there are male and ___________






Hermaphrodite

430 - In case of____________the presence of just one copy af allele results in the death of the individual






Dominant lethal allele

431 - In chlamydomonas str+mt+ x strsmt- , what will be the progeny






All str+

432 - In chlamydomonas strsmt+ x strsmt- , what will be the progeny






All str-

433 - In chlamydomonas there are _______mating types






2

434 - In conjugation process, the genes adjacent to__________ are transferred first






O

435 - In Danio rerio male is






None of these

436 - In Down syndrome about unusual ________characteristics are expressed






12 to 14

437 - In Drosophila melanogaster male is






XY

438 - In Drosophila, chaperones may function as






Heat -shock proteins

439 - In Drosophila, Males are_____________for sex linked genes






Hemizygous

440 - In Drosophila, only_________percent of the genome is occupied by genes coding for proteins.






10 to 15

441 - In Drosophilla, crossing over was shown to occur in_____________






female

442 - In E.coli the role of dnaB,C genes are to produce________at OriC






DNA helicase

443 - In E.coli the role of dnaE,N,Q,X,Z genes are to produce






DNA Polymerase III

444 - In E.coli the role of dnaG gene is to produce






RNA polymerase

445 - In E.coli the role of polA gene is to produce






DNA polymeraseI

446 - In E.coli the role of polB gene is to produce






DNA polynerase II

447 - In E.coli the role of repgene is to produce






DNA helicase

448 - In E.coli Type-I of topoisomerase reduces the_________supercoils into DNA






Negative

449 - In E.coli Type-II of topoisomerase introduces the_________supercoils into DNA






Negative

450 - In E.coli, elongation of transcription proceeds at the rate of________nucleotides/seconds at normal temperature






50

451 - In E.coli, there is only single replication origin called






oriC

452 - In early transformation studies, the effective length of transformed DNA was_________nucleotides






10000-20000

453 - In electrophoresis technique _________is used as medium






Agarose gel

454 - In Eukaryotes DNA ________ functions in repair of DNA single stranded breaks and the excision repair process






Lig 3

455 - In Eukaryotes DNA ________ is necessary for recombination and process called non-homologous end-joining






Lig 4

456 - In Eukaryotes DNA ________is the key ligase involved inDNA replication in mammalian cells






Lig 1

457 - In Eukaryotes each Okazaki fragment contain about__________nucleotides






100-500

458 - In eukaryotes the initial rRNA transcript is_______






45S

459 - In eukaryotes the monosome is a___________particle






80S

460 - In eukaryotes, sister chromatids are separated by






Topoisomerases

461 - In eukaryotes, many mRNAs contain a purine (A or G) three bases upstream from the AUG initiator codon is called






Kozak sequence

462 - In eukaryotes, the function of DNA polymerase alpha






RNA/DNA primer

463 - In eukaryotes, the function of DNA polymerase beta, theta and lambda






DNA repair

464 - In eukaryotes, the function of DNA polymerase delta






Lagging strand synthesis

465 - In eukaryotes, the function of DNA polymerase epsilon






Proof reading

466 - In eukaryotes, the function of DNA polymerase gamma






mtDNA replication

467 - In eukaryotes, the tail and cap of mRNA are held together with the help of initiation factor/factors






Both a and b

468 - In eukaryotes, there is/are ___________releasing factor/factors






1

469 - In eukaryotes, ubiquitin+misfolded proteins are digested by






Proteasome

470 - In eukaryotes,misfolded proteins are often tagged with small protein called






Ubiquitin

471 - In Eukaryotes,there is/are about________DNA ligase/ligses






3

472 - In Familial Down syndrome, one of the parent contains a






14/21

473 - In FMR1, the trinucleotide sequence _______is repeated in upstream region






CGG

474 - In fruit fly metamale and metafemale are






Infertile

475 - In fruit fly the sex determination is the control of






Both a and b

476 - In fruit fly, female with homozygous autosomal gene transformer(tra) will be






Sterile Male

477 - In fruit fly, male with homozygous autosomal gene transformer(tra) will be






Fertile Male

478 - In human _______carry two homologous x chromosomes






Metafemale

479 - In human abnormal sexual development(Klinefelter syndrome) has _________set of chromosomes






47, XXY

480 - In human abnormal sexual development(Turner syndrome) has _________set of chromosomes






45,X

481 - In human about_______million gametes are possible






8

482 - In human and many other species, there are________different aminoacyl tRNA synthetase






20

483 - In human arrested meiosis resumes in each oocyte just prior to its _________






Ovulation

484 - In human during oogenesis, the second division is completed only after_________






Fertilization

485 - In human inactivated X chromosome is also called






Both a and b

486 - In human intestinal cells APOB mRNA editing produces a single C to____change which converts a glutamine into a stop codon






U

487 - In human pattern baldness genotype BB will produce baldness in ___________






Male and female

488 - In human pattern baldness genotype Bb will produce baldness in ___________






Male

489 - In human pattern baldness genotype bb will produce baldness in ___________






None of these

490 - In human the telomeric sequence _____________repeated several thousand times






5-TTAGGG-3

491 - In human, about ________percent of human protein-coding genes have introns






94

492 - In Human, only_________percent of the genome is occupied by genes coding for proteins.






2

493 - In human, the probability of linkage in pedigree is calculated by__________method






Lod score

494 - In humans, the first division of all oocytes begins in the embryonic ovary but arrest in






Prophase1

495 - In inherited disorder(Tay-sachs), the patiant dies at the age of






3 year

496 - In leghorn breed, the feathering genotype__________has become fixed






hh

497 - In Lesh-Nyhan syndrome inherited as x-linked recessive disease, the nitogenous__________bases can not be salvage






Purines

498 - In Marfan syndrome in human dislocation of _________occurs






Lenses

499 - In meiosis chromosomes become short and thick in






Metaphase1

500 - In meiosis I spindle fiber attach with_________side/sides of kinetochore






One

501 - In meiosis II each gamete or spore receives_________chromatid/chromatids from each tetrad






1

502 - In meiosis II spindle fiber attach with_________side/sides of kinetochore






Both

503 - In meiosis nucleolus and nuclear membrane disappear in






Prophase1

504 - In Meselson and Stahl experiment the first generation of bacteria having heavy isotope of N during centrifuge will form band/bands in the______of test tube when grown in normal N containing medium






Middle

505 - In Meselson and Stahl experiment the second generation of bacteria having heavy isotope of N during centrifuge will form band/bands in the______of test tube when grown in normal N containing medium






Middle and top

506 - In Meselson and Stahl experiment the third generation of bacteria having heavy isotope of N during centrifuge will form band/bands in the______of test tube when grown in normal N containing medium






Middle and top

507 - In Meselson and Stahl experiment, which of the theory/theories could be ruled out after one round of replication






Cosevative

508 - In Meselson and Stahl experiment, which of the theory/theories could be ruled out after two rounds of replication






Dispersive

509 - In mitosis _______daughter cells are produced in one complete cell cycle






2

510 - In mitosis cohesin protein is degraded by an enzyme






Separase

511 - In molecular hybridization of nucleic acid DNA hybridize with________






Both a and b

512 - In most animals including humans, mtDNA cosists of






16-18 kb

513 - In most eukaryotes member of each species have________chromosomes in most of their cells






2n

514 - In most plant species, the Gametophyte is






Haploid

515 - In most plant species, the sporophyte is






Diploid

516 - In MST and PNT methods, the mtDNA is taken from






Donor

517 - In Musmusculus male is






XY

518 - In pedigree for human inheritance, circles represent






Female

519 - In pedigree for human inheritance, diamond represent






Sex unknown

520 - In pedigree for human inheritance, each generation is indicated by____________number






Roman

521 - In pedigree for human inheritance, fraternal or dizygotic twins, the sibling line is connected by_________line






Diagonal

522 - In pedigree for human inheritance, Identical or monozygotic twins, the diagonal lines are connected by_________line






Horizontal

523 - In pedigree for human inheritance, if parents are related, such as first cousins, are indicated by ___________line/lines






Double horizontal

524 - In pedigree for human inheritance, parents are indicated by single _______________line






Horizontal

525 - In pedigree for human inheritance, siblings are indicated by _______________line






Vertical

526 - In pedigree for human inheritance, sibs are placed in birth order from






Left to right

527 - In pedigree for human inheritance, squares represent






Male

528 - In pedigree for human inheritance, twins are indicated by _______________lines






Diagonal

529 - In pedigree for human, haded circles, squares and diamond represent_____________individuals






Affected

530 - In plants megaspore after germination produces






Female gametophyte

531 - In plants microspore after germination produces






Male gametophyte

532 - In Porphyria variegata , afflicted individuals can not adequately mrtabolize the






Porphyrin

533 - In Sacharomyces cervisiae, the gene fot mutant colony (petite) with small size colony locate on






Mitochondria

534 - In Sacharomyces cervisiae, the gene fot mutant colony (petite) with small size colony was discovered by






Ephrussi

535 - In Sacharomyces cervisiae, the mutant colony with small size is called






Petite

536 - In Seabright bantams breed, the feathering genotype__________has become fixed






HH

537 - In serial dilution minimum amount of sample required in ml






1

538 - In sickle cell anemia, valine was substituted for________ at the sixth position of the ÃŽ² chain






Glutamic acid

539 - In Somatic cell Hybridization, When a common cytoplasm contains different nuclei is called






Heterkaryon

540 - In Somatic cell Hybridization, When a different nuclei fuse together will form






Synkaryon

541 - In some eukaryotic genes, a cis-acting element within the core promoter is the __________






Both a and b

542 - In some eukaryotic genes, a cis-acting element within the core promoter is the TATA box, located about ______uncleotides pairs upstream






30

543 - In some reptiles_________ may has/have a great influenced on sex detrmination






Temperature

544 - In some_________RNA acts as genetic materia






Viruses

545 - In Temperature dependant sex determination, temoerature can not effect the follwing enzyme/hormone






Thyroxine

546 - In the 1960s, a new technique_____________proved to be successful in assigning genes to specific chromosomes






Somatic cell Hybridization

547 - In the bacteria, the DNA polymerase I is single polypeptide containing__________amino acids






928

548 - In the bacteria,the______is believed to be responsible for removing the primer and filling of gaps






DNA Polymerase I

549 - In the bacteria,which of the following enzyme is envolved in 5 to 3 polymerization






All of these

550 - In the bacteria,which of the following enzyme is/are complex






DNA Polymerase III

551 - In the glutamate receptor channels(GluR) mRNA editing Adenosine to __________editing occurs in mammalian brain tissues






I(inosine)

552 - In the peoples with phenylketonuria, blood level of phenylalanine is about_______mg/100ml






50

553 - In their initial experiments, Nirenberg synthesized________________ to decipher genetic code






RNA homopolymers

554 - In tissue culture dishes, normal human fibroblasts become senscent after about _________ cell divisions






50

555 - In vipers, the female is






Heterogametic

556 - In Xenopus laevis female is






ZW

557 - Increase in distance between two genes, __________the chance of parental gametes






Decreases

558 - Increase in distance between two genes, __________the chance of recombinant






Increases

559 - Increase in sample size, the average deviation from the expected results__________in Mendelian genetics






Decreases

560 - Individual bands are also called






Chromomeres

561 - Individuals having between________CGG repeat in FMR gene of fragile x syndrome(FXS) will be carrier






55-230

562 - Individuals having different genetic cell lines in somatic cells






Mosaics

563 - Individuals with mixture of karyotypes






Mosaics

564 - Initial phage density=( plaque number/mL x (______________)






Dilution factor

565 - Insertion/deletion editing in mRNA of trypanosomes is directed by






gRNA

566 - Interference ____________with increase in distance between two genes






Decreases

567 - Intersexuality is found in






Klinefelter syndrome

568 - Johan Mendel was born in






1822

569 - Klinefelter syndrome occurs in 1 of every female births






2000

570 - Klinefelter syndrome occurs in 1 of every male births






660

571 - Lactose intolerance is example of____________mutation






Nutritional

572 - Larger chromosome in trisomy condition cause_______ genetic imbalance in plants than smaller one.






Greater

573 - Less than________CGG repeat in FMR gene of fragile x syndrome(FXS) produce normal individuals






54

574 - Linear DNA is found in mitocondria of some






Ciliated protozoans

575 - LINEs costitute about_________percent of the human genome






21

576 - Lod score method was demonstrated by






Haldane

577 - Majority of ________fetuses die in uteri






45,X

578 - Mammalian cell contains____________of DNA polymerase molecules






20000-100000

579 - Mammalian genomes have as many as ____________replication origins






25000

580 - Many genes present on same chromosome, and they may indeed be transmitted as a single unit is called






Linkage

581 - Mapping in time units, in strain K12 is_______minutes long






100

582 - Maternal effect is due to herrdity of






Both a and b

583 - Mendel died of a________disorder






Kidney

584 - Mendel followed _________contasting traits in his experiments






7

585 - Mendel published his paper showing how traits were passed from generation to genration in






1866

586 - Mendel used the term of _________for allele






Factor

587 - Mendel's unit facrors represent units of inheritance called






Gene

588 - Microcephaly, cleft palate, Polydactyly and deformed finger nails are symptoms of






Patau

589 - Micronucleoli are found in the nucleus of






Oocyte

590 - Microsatellites appears throughout the genome approximately every________bases on average






10000

591 - Milk yield in dairy cattle is example of






Sex limited inheretance

592 - Milk yielding genses in dairy cattle are found in






Male and female

593 - Mirabilis jalapa variant have________leaves






All of these

594 - Misfolded proteins in bacteria are digested by






ATP dependent proteases

595 - Mitochondrial inheretance in Neurospora crasa was discovered by






Mary B Mitchel

596 - Mitochondrial ribosomes differ in size from______to_______






55-80

597 - Mitotic cells are fixed to slides and then subjected to hybridization is called _________molecular hybridization






In situ

598 - More than _________bacteriophage are produced per milliliter of culture medium






1010

599 - More than 90 percent of human ________cells contain telomerase activity






Cancer

600 - More than one polypeptide chains is characteristic of






Quarternary structure

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