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Skin and Vesiculobullous Lesion Problems Important MCQs

1 - A 3-year old patient has extensive vesicles on lip, tongue, oral mucous membrane, After 2-4 days vesicles rupture at followed by pseudomembrane formation and also some dermal lesions seen what will be the diagnosis?






EM

2 - A 40 year old woman report with the complaint of burning sensation in the mouth. Clinical examination reveals lesions consisting of radiating white striations in a retiform arrangement affecting buccal mucosa, tongue, lips & gingiva bilaterally. An incisional biopsy is suggestive of lichen planus. The following are different clinical forms of lichen planus except:






Verrucous lichen planus

3 - A 60 year old has got severe bulla and target lesion Which erythema around halo and genital lesions:_____________?






Stevens Jhonson syndrome

4 - A fluid filled elevated lesion of skin is called___________?






Bulla

5 - All are diseases of skin except:






Erythema migrans

6 - All of the following are inherited disorders of connective tissue EXCEPT:






McArdle's disease

7 - All of the following lesions may be classified as Odontogenic Tumours EXCEPT:






Branchial cleft cyst

8 - Antinuclear antibodies are seen in:___________?






SLE

9 - Bullae formation after striking an intact skin/mucosal surface is known as:__________?






Nikolsky's sign

10 - Butterfly rash is typically seen in:____________?






Systemic lupus erythematosus

11 - Cafe au lait macules are seen in:___________?






All of the above

12 - Darier's disease is associated with:____________?






Vitamin A deficiency and involvement of oral epithelium and skin

13 - Ectodermal dysplasia is:___________?






X-linked recessive

14 - Ehlers Danlos syndrome is__________?






Autosomal Dominant

15 - Erosive lichen planus resembles which of the following:






Desquamative gingivitis

16 - Erythema multiformae is:___________?






An acute self limiting disease, of skin and oral mucous membrane

17 - Fine Needle aspiration biopsy is indicated to diagnose:_____________?






Pemphigus

18 - Fish Net pattern is pemphigus vulgaris is seen in which of the following tests?






Direct immunofluorescence

19 - Formation of multiple pinpoint bleeding spots on scratching the skin is characteristic of:__________?






Psoriasis

20 - Grinspan syndrome is associated with:_________?






Hypertension, diabetes, lichen planus

21 - Grinspan syndrome is associated with:___________?






Lichen planus

22 - Histological clefts in lichen planus are____________?






Max – Joseph spaces

23 - Histopathological study of lichen planus shows:___________?






Presence of T-lymphocytes predominantly

24 - Hydropic degeneration of the basal cell of the straturn germinativum is a feature of___________?






Lichen planus

25 - Immunoflourescence is seen at basement membrane as patchy distribution in:___________?






Pemphigoid

26 - Immunoflourescence test is positive in:____________?






Both B & C

27 - In Cicatrial pemphigoid, which antigen is bound by IgG on the epidermal side of the salt split skin technique:___________?






XVII collagen

28 - In ectodermal dysplasia all of the following structures are affected except:___________?






Nails

29 - In lichen planus the basal cells which are shrunken with an eosinophilic cytoplasm and with a pyknotic and fragmented nuclei are called__________?






Civatte bodies

30 - In which of the following disorders a circulating antibody directed to intercellular cementing substance of stratified squamous epithelium is observed:_________?






Pemphigus vulgari

31 - Intra-epithelial bulla are found in:__________?






pemphigus

32 - Intraepithelial vacuolation with formation of vesicle or bulla intraepithelially above the basal layer is characteristically seen in:___________?






Pemphigus

33 - joint erosions are not a feature of:____________?






Systemis lupus eythematosus

34 - Koebner's phenomenon is seen with_____________?






Psoriasis

35 - L.E Cell phenomenon in peripheral blood is seen in:__________?






Systemic Lupus Erythematosus

36 - Lichen planus:____________?






Can undergo malignant change

37 - Lichenoid reactions are mainly due to:____________?






intake of certain drugs

38 - Lupus erythematosus is:____________?






Autoimmune disorder

39 - MONRO's abscess are seen in:____________?






Psoriasis

40 - Mucocutaneous lesions associated with neoplasia____________?






Paraneoplastic pemphigus

41 - Multiple pulp stones are seen in:_____________?






Ehler's Danlos syndrome

42 - Nikolsky's sign in positive in:_____________?






bullous pemphigus

43 - Oral diagnostic features of scleroderma include all of the following, except:__________?






Widening of the oral aperture

44 - Oral lesion associated with ulcerative colitis?






pyostomatitis vegentanus

45 - Oral lesions are not seen in:_________?






Psoriasis

46 - Oral ocular and genital lesions are seen in:__________?






Steven Johnson syndrome

47 - Pathologic calcification is seen in:__________?






Scleroderma

48 - Pemphigus is characterized by:____________?






Acantholysis

49 - Primary lesion in lichen planus is:___________?






Papule

50 - Psoralane Ultraviolet A (PUVA) therapy is advised in__________?






Pemphigus vulgaris

51 - Psoriasis is associated with:____________?






Geographic tongue

52 - Scleroderma involves:__________?






All of the above

53 - Steven-Johnson syndrome involves:____________?






Type III hypersensitivity reactions

54 - Subepithelial vesicles are characteristic all of the following EXCEPT:






Pemphigus

55 - Target lesions are observed in case of:___________?






Erythema multiforme

56 - The primary cause of acantholysis in pemphigus vulgaris is___________?






auto immunity

57 - The swollen degenerating epithelial cell due to acantholysis is:__________?






Tzanck cell

58 - Tzancks smear test is used in the diagnosis of___________?






pemphigus

59 - Unusual extensibility of the tongue is a characteristic feature of:__________?






Ehlers-Danlos syndrome

60 - Which is a degeneration disorder characterized by atrophic changes of the deeper structures (e.g fat, muscle, cartilage & bone) involving one side of the face:






Parry Romberg syndrome

61 - Which of the following are seen in ectodermal dysplasia?






Any of the above

62 - Which of the following diseases of the skin is the most likely to be associated with partial anodontia?






hereditary actodermal dysplasia

63 - Which of the following is absent in Crest syndrome






Endocrine disorders

64 - Which of the following is an oral manifestation of lichen planus?






White radiating lines on the buccal mucosa

65 - Which of the following is inherited as a autosomal dominant triat?






White sponge nevus

66 - Which of the following is not a type of lichen planus?






Verrucous

67 - Which sites are characteristically affected in Stevens-Johnson syndrome?






Conjunctive, genitalia, oral mucosa

68 - White radiating lines can be observed in case of lesions of:___________?






Lichen planus

69 - Wickham's striae are seen in:__________?






Lichen planus

70 - Xeroderma pigmentosum is characterized by:___________?






Inability to repair sunlight induced damage to DNA

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