1 - A 14 year old boy complains with gingival bleeding oral ulcers, anaemia with hepatomegaly but no lymphadenopathy, total eukocyte count of one-lakh cells per mm3 is suffering from________________?
1 - A 14 year old boy complains with gingival bleeding oral ulcers, anaemia with hepatomegaly but no lymphadenopathy, total eukocyte count of one-lakh cells per mm3 is suffering from________________?
Acute myeloid leukemia
2 - A 20 year male complains of recurrent attacks of sore tthroat since 2 years. The total leukocyte count was 1000/ul. A differential count revealed severe neutropenia. The diagnosis is________________?
2 - A 20 year male complains of recurrent attacks of sore tthroat since 2 years. The total leukocyte count was 1000/ul. A differential count revealed severe neutropenia. The diagnosis is________________?
Agraulocytosis
3 - A 3-year old child presented with progressive anaemia, jaundice & failure to thrive. O/E: pallor, splenomegaly are seen Peripheral smear showed normoblasts and small round intensely stained red cells. The likely diagnosis is________________?
3 - A 3-year old child presented with progressive anaemia, jaundice & failure to thrive. O/E: pallor, splenomegaly are seen Peripheral smear showed normoblasts and small round intensely stained red cells. The likely diagnosis is________________?
Here ditary spherocytosis
4 - A patient with a bleeding disorder with increased bleeding time and normal clotting time is suffering from________________?
4 - A patient with a bleeding disorder with increased bleeding time and normal clotting time is suffering from________________?
Idiopathic thrombocytopenic purpura
5 - A patient's urine with a particular protein appears normal, but on standing it becomes dark. The dark colour disappears on heating. The patent is suffering from______________?
5 - A patient's urine with a particular protein appears normal, but on standing it becomes dark. The dark colour disappears on heating. The patent is suffering from______________?
Multiple myeloma
6 - A shift to left indicates an increase in number of______________?
6 - A shift to left indicates an increase in number of______________?
immature neutrophils
7 - A simple bacterial test for mutagenic carcinogens is________________?
7 - A simple bacterial test for mutagenic carcinogens is________________?
Ames test
8 - Active hypermia is seen in_______________?
8 - Active hypermia is seen in_______________?
All of the Above
9 - After myocardial infarction all of the following enzyme levels are high except_____________?
9 - After myocardial infarction all of the following enzyme levels are high except_____________?
Serum ornithine carbamyl transferase (SOCT)
10 - All of the following are typically associated with loss of 40% of the circulating blood volume except_______________?
10 - All of the following are typically associated with loss of 40% of the circulating blood volume except_______________?
A decrease in the heart rate
11 - All of the following can be transmitted through blood tranfusion except ______________?
11 - All of the following can be transmitted through blood tranfusion except ______________?
Leukemia
12 - All of the following causes excessive bleeding during tooth extraction except _______________?
12 - All of the following causes excessive bleeding during tooth extraction except _______________?
Anti thrombin – III deficiency
13 - All of the following differs antemortum thrombus from a postmortem intravascular costs except_____________?
13 - All of the following differs antemortum thrombus from a postmortem intravascular costs except_____________?
Chicken fat appearance
14 - All of the following statements are true regarding reversible cell injury, except______________?
14 - All of the following statements are true regarding reversible cell injury, except______________?
Formation of amorphous densities in the mitochondrial matix
15 - All of the following viruses are capable of causing human cancers except________________?
15 - All of the following viruses are capable of causing human cancers except________________?
Parvovirus B-19
16 - Amyloid material can be best diagnosed by___________________?
16 - Amyloid material can be best diagnosed by___________________?
Polarized microscopy
17 - An infarct is most frequently is characterized by What type of necrosis ?
17 - An infarct is most frequently is characterized by What type of necrosis ?
Coagulative
18 - Anaplasia is_______________?
18 - Anaplasia is_______________?
All of the above
19 - Anasarca means_____________?
19 - Anasarca means_____________?
Severe generalized swelling
20 - Aplastic anemia results from______________?
20 - Aplastic anemia results from______________?
All of the above
21 - Ascites seen in alcoholic liver cirrhosis result form______________?
21 - Ascites seen in alcoholic liver cirrhosis result form______________?
Decreased protein production by liver
22 - Auto immune hymolytic anemia is seen in_______________?
22 - Auto immune hymolytic anemia is seen in_______________?
CLL
23 - Basal cell carcinoma occurs on_________________?
23 - Basal cell carcinoma occurs on_________________?
Skin and pilosebaceous adnexa
24 - Both Pala or red infarcts are seen in______________?
24 - Both Pala or red infarcts are seen in______________?
Brain
25 - Burkitt's lymphoma is associated with the proliferation of ______________?
25 - Burkitt's lymphoma is associated with the proliferation of ______________?
B – cell
26 - Caissons disease is caused by______________?
26 - Caissons disease is caused by______________?
Air or gas embolism
27 - Carcinogens induce tumours, they are________________?
27 - Carcinogens induce tumours, they are________________?
All of the above
28 - Change in structure and functions of a tissue is called______________?
28 - Change in structure and functions of a tissue is called______________?
Metaplasia
29 - Chicken-wire appearance of enlarged bone marrow spaces is seen in_______________?
29 - Chicken-wire appearance of enlarged bone marrow spaces is seen in_______________?
Beta thalassemia majon
30 - Cooley's anemia is also called___________________?
30 - Cooley's anemia is also called___________________?
All of the above
31 - Cotton wool appearance is seen ____________________ ?
31 - Cotton wool appearance is seen ____________________ ?
Pagets disease
32 - Deposition of bile pigment in the basal ganglia is called________________?
32 - Deposition of bile pigment in the basal ganglia is called________________?
Kernicterus
33 - Earliest lesion in atherosclerosis is_____________?
33 - Earliest lesion in atherosclerosis is_____________?
Fatty streak
34 - Edema is due to_______________?
34 - Edema is due to_______________?
Decreased albumin conc. in blood
35 - Epstein Barr virus is associated with ___________________?
35 - Epstein Barr virus is associated with ___________________?
All of the above
36 - Erythroblastosis fetalis is a condition seen when there is________________?
36 - Erythroblastosis fetalis is a condition seen when there is________________?
Rh -ve mother and Rh +ve foetus
37 - Exfoliative cytology is indicated in___________?
37 - Exfoliative cytology is indicated in___________?
Mass screening of cervical cancer
38 - Extravasation of blood in to the tissues with resulting swelling is called_____________?
38 - Extravasation of blood in to the tissues with resulting swelling is called_____________?
Hematoma
39 - Following is the most important factor in the management of shock_________________?
39 - Following is the most important factor in the management of shock_________________?
Deficiency of effective circulating blood volume
40 - Gamma gandy bodies are seen in_____________?
40 - Gamma gandy bodies are seen in_____________?
Spleen
41 - Gingiva are enlarged in leukemia because of____________________?
41 - Gingiva are enlarged in leukemia because of____________________?
Hemolytic anaemia
42 - Heart failure cells are seen in_______________?
42 - Heart failure cells are seen in_______________?
Lungs
43 - Heart failure cells are____________?
43 - Heart failure cells are____________?
Heamosiderin laden macrophages in alveoli
44 - Hemophilia A is caused due to deficiency of___________________?
44 - Hemophilia A is caused due to deficiency of___________________?
Factor VIII
45 - Hemophilics show_________________?
45 - Hemophilics show_________________?
Normal bleeding time and increased clotting time
46 - Hodgkin's lymphoma can be distinguished from non – Hodgkin's lymphomas by_________________?
46 - Hodgkin's lymphoma can be distinguished from non – Hodgkin's lymphomas by_________________?
All of the above
47 - Hypovolemic shock develops after loss of______________?
47 - Hypovolemic shock develops after loss of______________?
40% blood
48 - Immune response to tumour is mediated by_______________?
48 - Immune response to tumour is mediated by_______________?
All of the above
49 - In a thrombus, the dark lines of zahn are due to_______________?
49 - In a thrombus, the dark lines of zahn are due to_______________?
Aggregated R.B.C
50 - In dysplasia mitotic figures are seen in_________________?
50 - In dysplasia mitotic figures are seen in_________________?
From basal layer to surface
51 - IN fanconi anemia there is a_______________?
51 - IN fanconi anemia there is a_______________?
Mutation of DNA repair gene
52 - In hemorrhager lost plasma is replaced by______________?
52 - In hemorrhager lost plasma is replaced by______________?
Kidney
53 - In hypovolemic shock_____________?
53 - In hypovolemic shock_____________?
The extremities are pale, cold and sweating
54 - In left ventricular cardiac failure there is_____________?
54 - In left ventricular cardiac failure there is_____________?
Passive Congestion in lungs
55 - In sickle cell anaemia there is_____________?
55 - In sickle cell anaemia there is_____________?
75 to 100% haemoglobins
56 - In Troisiers sign the lymph nodes involved are_________________?
56 - In Troisiers sign the lymph nodes involved are_________________?
Left supraclavicular nodes
57 - In which one of the following organs the venous emboli are most often iodged ?
57 - In which one of the following organs the venous emboli are most often iodged ?
Lungs
58 - Incidence of most common malignant tumours in women is_____________?
58 - Incidence of most common malignant tumours in women is_____________?
Breast
59 - Increased bleeding time is seen in all except______________?
59 - Increased bleeding time is seen in all except______________?
Hemophilia
60 - Increased iron binding capacity and decreased serum iron is seen in which anemia________________?
60 - Increased iron binding capacity and decreased serum iron is seen in which anemia________________?
Iron deficiency
61 - Increased levels of haemoglobin A2 is characteristic of________________?
61 - Increased levels of haemoglobin A2 is characteristic of________________?
b-thalassaemia crait
62 - Increased proliferation of cells is called_______________?
62 - Increased proliferation of cells is called_______________?
Hyperplasia
63 - Infarcts are not common in______________?
63 - Infarcts are not common in______________?
Both A and B
64 - Keratin pearls with downward proliferation of epithelial masses is characteristic of_______________?
64 - Keratin pearls with downward proliferation of epithelial masses is characteristic of_______________?
Squamous cell carcinoma
65 - Left side heart failure results in______________?
65 - Left side heart failure results in______________?
Oedema of lungs
66 - Lymphatic leukemoid reaction is usually seen in the following EXCEPT________________?
66 - Lymphatic leukemoid reaction is usually seen in the following EXCEPT________________?
Lobar pneumonia
67 - Major and frequent influence for thrombus formation is________________?
67 - Major and frequent influence for thrombus formation is________________?
Endothelial damage
68 - Major site of atheroscierosis_______________?
68 - Major site of atheroscierosis_______________?
Abdominal aorta
69 - Malignant neoplasms shows all the following features EXCEPT_____________?
69 - Malignant neoplasms shows all the following features EXCEPT_____________?
Encapulation
70 - Malignant tumour of epithelial origin is_______________?
70 - Malignant tumour of epithelial origin is_______________?
Carcinoma
71 - Malignant tumour of skeletal muscie is__________________?
71 - Malignant tumour of skeletal muscie is__________________?
Rhabdomyosarcoma
72 - Most tumours are ___________________?
72 - Most tumours are ___________________?
Monoclonal in origin
73 - Neoplasia of blood vessel is called______________?
73 - Neoplasia of blood vessel is called______________?
Angioma
74 - Neurologic abnormalities occur with_______________?
74 - Neurologic abnormalities occur with_______________?
Both B and C
75 - Nevus cell are_______________?
75 - Nevus cell are_______________?
Modified melanocytes
76 - Normal adult haemoglobin contains________________?
76 - Normal adult haemoglobin contains________________?
Two alpha chains and two beta chains
77 - Nuclear cytoplasmic ratio in malignant cells is________________?
77 - Nuclear cytoplasmic ratio in malignant cells is________________?
0.042361111111
78 - Nut meg liver occurs in_______________?
78 - Nut meg liver occurs in_______________?
Chronic venous congestion
79 - Oncogenic viruses in human are_________________?
79 - Oncogenic viruses in human are_________________?
All of the above
80 - One of the following is not a malignant feature____________?
80 - One of the following is not a malignant feature____________?
Pleomorphism
81 - Onion skin appearance is seen in_______________?
81 - Onion skin appearance is seen in_______________?
Ewing's sarcoma
82 - Osteomalacia is associated with_________________?
82 - Osteomalacia is associated with_________________?
Increase in osteoid maturation time
83 - Pale infarcts are seen in all of the following except______________?
83 - Pale infarcts are seen in all of the following except______________?
Lung
84 - Pap smear is used to detect dysplasia, carcinoma insitu and invasive carcinoma of uterine cervix. This is based on the principle of_______________?
84 - Pap smear is used to detect dysplasia, carcinoma insitu and invasive carcinoma of uterine cervix. This is based on the principle of_______________?
Neoplastic cells are are non cohesive
85 - Partial or complete obstruction of some part of the C.V.S by a foreign body transported by the blood stream is termed as_____________?
85 - Partial or complete obstruction of some part of the C.V.S by a foreign body transported by the blood stream is termed as_____________?
Embolism
86 - Philadelphia chromosome is consistently found in_______________?
86 - Philadelphia chromosome is consistently found in_______________?
CML
87 - Primary hemostasis is disturbed in______________?
87 - Primary hemostasis is disturbed in______________?
Platelet disorder
88 - Prothrombin time indicates the integrity of ____________________?
88 - Prothrombin time indicates the integrity of ____________________?
Extrinsic pathway
89 - Reduced number of platelet is found in all the conditions except____________________?
89 - Reduced number of platelet is found in all the conditions except____________________?
Von willebrand disease
90 - Reed – Sternberg cells are seen in histopathological examination of_______________?
90 - Reed – Sternberg cells are seen in histopathological examination of_______________?
Hodgkin's disease
91 - Risk factor for atherosclerosis_______________?
91 - Risk factor for atherosclerosis_______________?
All of the above
92 - Rodent ulcer is most commonly seen on________________?
92 - Rodent ulcer is most commonly seen on________________?
Face above alatragus line
93 - Schilling test is performed to find out______________?
93 - Schilling test is performed to find out______________?
B12 malabsroption
94 - Shock is a circulatory disturbance characterized by________________?
94 - Shock is a circulatory disturbance characterized by________________?
Decreased volume of circulation blood
95 - Sickle cell anemia precipitates when______________?
95 - Sickle cell anemia precipitates when______________?
Increased viscosity of blood
96 - Sideroblastic anemia is caused due to______________?
96 - Sideroblastic anemia is caused due to______________?
Iron
97 - Somatic mutation of PTEN is seen in________________?
97 - Somatic mutation of PTEN is seen in________________?
Endometrial Carcinoma
98 - Sunburst appearance and codmans triangle are seen in______________?
98 - Sunburst appearance and codmans triangle are seen in______________?
Osteosarcoma
99 - Syndrome associated with increased risk of leukemia is_____________?
99 - Syndrome associated with increased risk of leukemia is_____________?
Klinefelter syndrome
100 - Target cells are seen in peripheral blood in_______________?
100 - Target cells are seen in peripheral blood in_______________?
Thalassemia
101 - The cell with increased mitotic rate and resembling the undifferentiated mesenchymal cells of the same origin is______________?
101 - The cell with increased mitotic rate and resembling the undifferentiated mesenchymal cells of the same origin is______________?
Anaplastic
102 - The characteristic finding in chronic myeloid leukemia is______________?
102 - The characteristic finding in chronic myeloid leukemia is______________?
Reduced score of alkaline phosphatase in granulocytes
103 - The common cause of sudden death in myocardial infarction is____________?
103 - The common cause of sudden death in myocardial infarction is____________?
Arrhythmias
104 - The commonest site of thrombosis is_______________?
104 - The commonest site of thrombosis is_______________?
Veins
105 - The fading of cellular chromatin is_____________?
105 - The fading of cellular chromatin is_____________?
Karyolysis
106 - The following are recognized causes of neutropenia Except_______________?
106 - The following are recognized causes of neutropenia Except_______________?
Corticosteroid therapy
107 - The increase in size of individual cells is referred as______________?
107 - The increase in size of individual cells is referred as______________?
Hypertrophy
108 - The increase in size of uterus during pregnancy is an example of ________________?
108 - The increase in size of uterus during pregnancy is an example of ________________?
Both of the above
109 - The increase in the size of left kidney following the removal of right kidney (vicarious hypertrophy) is due to_______________?
109 - The increase in the size of left kidney following the removal of right kidney (vicarious hypertrophy) is due to_______________?
Both of the above
110 - The infarct of the following organs is invariably haemorrhagic_____________?
110 - The infarct of the following organs is invariably haemorrhagic_____________?
Lung
111 - the lesions of bone which is expansile and eccentrically ballooned out is________________?
111 - the lesions of bone which is expansile and eccentrically ballooned out is________________?
Aneurysmal bone cyst
112 - The major factors predisposing to thrombogenesis include all of the following except_____________?
112 - The major factors predisposing to thrombogenesis include all of the following except_____________?
Pattern of blood flow
113 - The most characteristic feature of a neoplasm as opposed to inflammatory over growth is______________?
113 - The most characteristic feature of a neoplasm as opposed to inflammatory over growth is______________?
Progressive growth after removal of causative stimuli
114 - The most common site of metastases of osteosarcoma is_____________?
114 - The most common site of metastases of osteosarcoma is_____________?
Lung
115 - The most common site of origin for venous thrombi leading to pulmonary embolism is_____________?
115 - The most common site of origin for venous thrombi leading to pulmonary embolism is_____________?
Deep leg veins
116 - The most definite feature of a malignant tumour is_____________?
116 - The most definite feature of a malignant tumour is_____________?
Metastasis
117 - The most reliable post mortem features of left sided cardiac failure is____________?
117 - The most reliable post mortem features of left sided cardiac failure is____________?
Chronic venous congestion of lungs
118 - The necrotic tissue and deposits of immune complexes, complement and plasma protein produce a smudy eosinophilic deposit is termed as_____________?
118 - The necrotic tissue and deposits of immune complexes, complement and plasma protein produce a smudy eosinophilic deposit is termed as_____________?
Fibrinoid necrosis
119 - The predisposing factor for squamous cell carcinoma __________________?
119 - The predisposing factor for squamous cell carcinoma __________________?
All of the above
120 - The process of formation of solid mass in circulation from the constituents of normal flowing blood is called_____________?
120 - The process of formation of solid mass in circulation from the constituents of normal flowing blood is called_____________?
Thrombosis
121 - The protein that carries iron from the gut to the body tissues is called________________?
121 - The protein that carries iron from the gut to the body tissues is called________________?
Transferrin
122 - The type of acute myelogenous leukemia associated with a high incidence of disseminated intravascular coagulation in________________?
122 - The type of acute myelogenous leukemia associated with a high incidence of disseminated intravascular coagulation in________________?
Acute promyelocytic leukaemia
123 - The type of embolism seen in fractures of long bones_____________?
123 - The type of embolism seen in fractures of long bones_____________?
Fat embolism
124 - The wasting syndrome associated in cancer is_____________?
124 - The wasting syndrome associated in cancer is_____________?
Cacchexia
125 - Three days after the onset of myocardial infarction, which enzyme level has the best predictive value____________?
125 - Three days after the onset of myocardial infarction, which enzyme level has the best predictive value____________?
Serum LDH
126 - Thrombocytopenia due to increased platelet destruction is seen in_________________?
126 - Thrombocytopenia due to increased platelet destruction is seen in_________________?
Systemic lupus erythematosus
127 - Thrombocytosis is seen in_______________?
127 - Thrombocytosis is seen in_______________?
Haemolytic anaemia
128 - Thrombosis due to hypercoagulability is seen in____________?
128 - Thrombosis due to hypercoagulability is seen in____________?
All of the above
129 - Tumour arising from secetory and glandular epithelium are__________________?
129 - Tumour arising from secetory and glandular epithelium are__________________?
Both A and B
130 - Tumour which shows origin from more than one germ layers is known as________________?
130 - Tumour which shows origin from more than one germ layers is known as________________?
Teratoma
131 - Usually metastatic lesions are osteolytic, but osteoblastic secondaries occur in cancer of_______________?
131 - Usually metastatic lesions are osteolytic, but osteoblastic secondaries occur in cancer of_______________?
Prostate
132 - Venous emboli are most often lodged in_____________?
132 - Venous emboli are most often lodged in_____________?
Lungs
133 - Which of the following being is the most frequent site of thrombus ?
133 - Which of the following being is the most frequent site of thrombus ?
Veins of lower extremities
134 - Which of the following is a nutritional deficiency anemia______________?
134 - Which of the following is a nutritional deficiency anemia______________?
megaloblastic anemia
135 - Which of the following is common in all forms of shock ?
135 - Which of the following is common in all forms of shock ?
Impaired tissue prefusion
136 - Which of the following is correct statement ?
136 - Which of the following is correct statement ?
All of the above
137 - Which of the following is correctly matched with the forms of extravasation hemorrhages______________?
137 - Which of the following is correctly matched with the forms of extravasation hemorrhages______________?
All of the above
138 - Which of the following is not an example of massive splenomegaly ________________?
138 - Which of the following is not an example of massive splenomegaly ________________?
Acute lymphoblastic leukemia
139 - Which of the following is not an indicative of hemorrhage_____________?
139 - Which of the following is not an indicative of hemorrhage_____________?
Melanosis
140 - Which of the following is not true for hemophilia A ________________?
140 - Which of the following is not true for hemophilia A ________________?
Levels of factor VIII less than 50% are associated with spontaneous hemorrhage
141 - Which of the following predisposes to thrombogenesis ?
141 - Which of the following predisposes to thrombogenesis ?
All of the above
142 - Which of the following symptomatic atheroscierotic disease is correct_____________?
142 - Which of the following symptomatic atheroscierotic disease is correct_____________?
All of the above
143 - White infarcts occurs in one of the following organs_______________?
143 - White infarcts occurs in one of the following organs_______________?
Heart
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